@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : KS6A1_HUMAN: (2021-11-23 )
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKDEGVLKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKLPSTTL
Atome Classification :
(386 SA)
-------------------------------------------------------------------------------------------------------.........10........20........30........40.--.......50..-......60------........70-........80........90.....-..-.-100-.--.-.-.-..-.-.110.....-.--..----120-..-.......130.......140.......150...--....160.......170.......180........190....-...200.....-.------------------------------.210.-...-..-----.220.........230...-----..---.-----.240.......250......-.260---.---..----....----270------...--..--..--280--.--..---.....290.......300.--......-310...-.....320...---....330.......340.......350.....---.----.360--...--.--.---.--.--.370----........380.......390.......400.......410.......420.......430.......440.......450.......460-.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690........700.......710.......720.......730...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------MPLAQLKEPWPL
M
E
LVPLDPENGQTSGEEAGLQPSKDE
G
V
L
K
--
E
I
S
I
T
H
H
VKAG-SEKAD
P
S
H
------
F
E
L
L
K
V
L
GQG-SF
G
K
V
F
L
V
R
K
VTRPDSG
H
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-A--DV----N---H
P
-
F
V
V
K
L
H
Y
A
FQTE
G
K
L
Y
L
I
L
D
F
LRG
G
D
L
F
T
R
L
S
K
--
E
VMF
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
RDLKPE
N
I
L
LD-EEG
H
I
K
L
T
DFG-L------------------------------S
K
E
A
I
-
D
H
E
-
K
K
-----
A
Y
--
S
F
CG
T
V
E
Y
M
A
P
E
V
V
N-----RQ---G-----HSHS
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
TG-SLPF---Q---GK----DRK
E
----
T
M
T
------
L
I
L
--
K
A--KL--GM---
P
--
Q
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
KRN
P
A
N--RLGSGP-D-
G
A
E
E
-
I
K
R
H
V
FYSTI
D
---
W
N
K
L
Y
R
R
EIKPPFKPAVAQPDD
T
F
Y
FDTEFTS---R----TPK---DSP--G--I---P--P--SA
G
-----
A
H
Q
L
F
R
G
F
S
F
V
A
T
G
LMEDDGKPRAPQA
P
L
H
S
V
V
Q
Q
LHGK
N
L
VFSDG
Y
V
V
K
E
TIGVG
S
Y
S
E
C
K
R
C
V
H
K
AT
N
M
E
Y
A
V
K
V
I
DKSKRD
P
S
E
E
I
E
I
-
L
L
RYGQHP
N
I
I
T
L
KDVYDDG
K
H
V
Y
L
V
T
E
L
MR
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
SQG
V
V
HRDLKPS
N
I
L
Y
VDESGNP
E
C
L
R
I
CDF
G
F
A
K
Q
L
RAEN
G
L
L
MTPCYTANFV
A
P
E
V
L
K
RQGYDEGC
D
I
W
S
L
G
I
L
L
Y
T
M
L
AGYTPFANGPSD
T
P
E
E
I
L
T
R
IGS
G
K
F
T
LSGGNWN
T
V
S
E
T
A
K
D
L
V
S
K
M
LHVDPHQR
L
T
A
K
Q
V
L
QHPWVTQKDKL
P
Q
S
QLS
H
Q
D
L
-
Q
L
V
K
G
A
M
A
A
T
Y
S
A
LNSSKPTPQLKP
I
E
S
S
I
L
A
Q
R
R
V
R
KLPSTTL
576
HHSearch
83.96
100%
-96
- C3 -
-
4NIF
-
KS6A1_HUMAN
A:
[5-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
S
D
G
Y
V
V
K
E
T
I
G
V
G
S
Y
S
E
C
K
R
C
V
H
K
A
T
N
M
E
Y
A
V
K
V
I
D
K
S
K
R
D
P
S
E
E
I
E
I
-
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
C
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
L
M
T
P
C
Y
---
F
V
A
P
E
V
L
K
R
Q
G
Y
D
E
G
C
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
F
A
N
G
P
S
D
T
P
E
E
I
L
T
R
I
G
S
G
K
F
T
L
S
G
G
N
W
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
K
Q
V
L
Q
H
P
W
V
T
Q
K
D
K
L
P
Q
S
Q
L
S
H
Q
D
L
-
Q
L
V
K
G
A
M
A
A
T
Y
S
A
L
N
S
S
K
P
T
P
Q
L
K
P
I
E
S
S
I
L
A
Q
R
R
V
R
-------
1
PsiBlast_PDB
83.72
99%
-96
- C3 -
-
4NIF
-
KS6A1_HUMAN
A:
[5-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
S
D
G
Y
V
V
K
E
T
I
G
V
G
S
Y
S
E
C
K
R
C
V
H
K
A
T
N
M
E
Y
A
V
K
V
I
D
K
S
K
R
D
P
S
E
E
I
E
I
-
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
C
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
L
M
T
P
C
Y
---
F
V
A
P
E
V
L
K
R
Q
G
Y
D
E
G
C
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
F
A
N
G
P
S
D
T
P
E
E
I
L
T
R
I
G
S
G
K
F
T
L
S
G
G
N
W
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
K
Q
V
L
Q
H
P
W
V
T
Q
K
D
K
L
P
Q
S
Q
L
S
H
Q
D
L
-
Q
L
V
K
G
A
M
A
A
T
Y
S
A
L
N
S
S
K
P
T
P
Q
L
K
P
I
E
S
S
I
L
A
Q
R
R
V
R
-------
11
PsiBlast_PDB
82.89
86%
-103
- C3 -
-
4NUS
1
KS6A3_HUMAN
A:
[17-322]
-------------------------------------------------------------------------------------------------------------------------------------------------------
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
I
-
D
H
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
A
------
T
F
Y
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
82.61
86%
-88
- C3 -
-
4NW5
1
KS6A3_HUMAN
A:
[15-322]
-----------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
I
-
D
H
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-------
T
F
Y
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
82.55
86%
-90
- C3 -
-
4NW6
1
KS6A3_HUMAN
A:
[15-322]
-----------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
I
-
D
H
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-------
T
F
Y
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Blastp_CBE
80.76
86%
-114
- C3 -
-
6G77
2
KS6A6_HUMAN
B:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
-
R
-
D
------------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-
D
Q
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
M
N
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Blastp_CBE
80.02
86%
-110
- C3 -
-
6G77
2
KS6A6_HUMAN
A:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
-
R
-
D
------------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-
D
Q
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
M
N
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Blastp_CBE
79.60
86%
-110
- C3 -
-
6G76
2
KS6A6_HUMAN
A:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
-
R
-
D
------------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-
D
Q
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
M
N
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
79.59
86%
-89
- C3 -
-
5D9L
2
KS6A3_HUMAN
A:
[13-322]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
---------------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
A
T
G
R
P
E
D
T
F
Y
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Blastp_CBE
79.58
86%
-115
- C3 -
-
5D9K
2
KS6A3_HUMAN
B:
[26-323]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
--------------------
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
-------
T
F
Y
F
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
79.13
86%
-116
- C3 -
-
5D9K
2
KS6A3_HUMAN
A:
[26-323]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-
R
-
T
K
M
-
E
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
---------------------
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
A
------
T
F
Y
F
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Blastp_CBE
78.39
86%
-115
- C3 -
-
6G78
1
KS6A6_HUMAN
A:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
-
R
-
D
------------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-
D
Q
----------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
M
N
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
78.15
87%
-120
- C3 -
-
3G51
1
KS6A3_MOUSE
A:
[5-304]
-----------------------------------------------------------------------------------------------------------------------------------------------
I
K
--
E
I
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
---------------
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
I
--------------------
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Blastp_CBE
78.03
86%
-123
- C3 -
-
6G78
1
KS6A6_HUMAN
B:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
-
R
-
D
------------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-------------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
M
N
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Blastp_CBE
77.23
89%
-113
- C3 -
-
3UBD
1
KS6A3_MOUSE
A:
[7-304]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
---------
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
------
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Blastp_CBE
77.11
89%
-113
- C3 -
-
4EL9
1
KS6A3_MOUSE
A:
[8-305]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
--------
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
----
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Blastp_CBE
77.09
89%
-112
- C3 -
-
4GUE
1
KS6A3_MOUSE
A:
[7-305]
------------------------------------------------------------------------------------------------------------------------------------------------
K
--
E
I
A
I
T
H
H
V
K
E
G
-
H
E
K
A
D
P
S
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
K
I
S
G
S
D
A
R
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-
R
-
D
-
R
V
-----------
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
------
E
-
K
K
-----
A
Y
--
S
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
M
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
A
G
P
-
D
-
G
V
E
E
-
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
76.36
100%
-115
- C3 -
-
2Z7R
1
KS6A1_HUMAN
A:
[21-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
S
E
K
A
D
P
S
H
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
-
K
K
-
A
-
T
L
--
K
--
V
-----------------
I
L
-
A
--
D
V
----
N
---
H
P
-
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
---------------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
---
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
L
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
--
R
L
G
S
G
P
-
D
-
G
A
E
E
-
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
76.14
80%
-104
- C3 -
-
2QR8
-
A:
[19-316]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
T
D
G
Y
E
V
K
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
I
H
K
A
T
N
M
E
F
A
V
K
I
I
D
K
S
K
R
D
P
T
E
E
I
E
I
-
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
Y
V
Y
V
V
T
E
L
M
K
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
A
V
L
F
T
I
T
K
T
V
E
Y
L
H
A
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
S
I
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
L
M
T
P
C
Y
T
A
N
F
V
A
P
E
V
L
E
R
Q
G
Y
D
A
A
C
D
I
W
S
L
G
V
L
L
Y
T
M
L
T
G
Y
T
P
F
A
N
G
P
D
D
T
P
E
E
I
L
A
R
I
G
S
G
K
F
S
L
S
G
G
Y
W
N
S
V
S
D
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
A
L
V
L
R
H
P
W
I
V
H
W
D
Q
L
P
Q
Y
Q
L
N
R
Q
D
A
P
H
L
V
K
G
A
M
A
A
T
Y
S
A
L
N
R
N
Q
--------------------------
5
PsiBlast_PDB
75.90
100%
-123
- C3 -
-
2Z7S
1
KS6A1_HUMAN
A:
[24-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
P
S
H
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
-
K
-----------------------------
I
L
-
A
--
D
V
----
N
---
H
P
-
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
---------------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
---
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
L
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
--
R
L
G
S
G
P
-
D
-
G
A
E
E
-
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
75.67
100%
-125
- C3 -
-
2Z7Q
1
KS6A1_HUMAN
A:
[24-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
P
S
H
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
V
T
R
P
D
S
G
H
L
Y
A
M
K
V
L
-------------------------------
I
L
-
A
--
D
V
----
N
---
H
P
-
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
---------------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
---
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
S
L
P
F
---
Q
---
G
K
----
D
R
K
E
----
T
M
T
------
L
I
L
--
K
A
--
K
L
--
G
M
---
P
--
Q
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
--
R
L
G
S
G
P
-
D
-
G
A
E
E
-
I
K
R
H
V
F
Y
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Blastp_CBE
73.39
86%
-114
- C3 -
-
6G76
1
KS6A6_HUMAN
B:
[9-307]
----------------------------------------------------------------------------------------------------------------------------------------------
V
V
K
--
E
I
P
I
T
H
H
V
K
E
G
-
Y
E
K
A
D
P
A
Q
------
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
R
K
K
T
G
P
D
A
G
Q
L
Y
A
M
K
V
L
-
K
K
-
A
-
S
L
--
K
--
V
---------------
R
D
I
L
-
V
--
E
V
----
N
---
H
P
-
F
I
V
K
L
H
Y
A
F
Q
T
--
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
S
K
--
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
E
I
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
E
S
V
-
D
-------------------
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
-----
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
-
T
L
P
F
---
Q
---
G
K
----
D
R
N
E
----
T
------------------
L
--
G
M
---
P
--
Q
F
---
L
S
A
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
--
R
L
G
S
---
E
-
G
V
E
E
-
I
K
R
H
L
F
F
A
N
I
D
---
W
D
K
L
Y
K
R
E
V
Q
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Blastp_CBE
66.04
53%
2
- C3 -
-
4L44
1
KS6B1_HUMAN
A:
[10-344]
--------------------------------------------------------------------------------------------------------------------------------------------------------
R
----
G
-
P
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
-----------
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
-
D
S
K
F
T
R
---
Q
----
T
-----------------------
S
E
S
-----
A
N
Q
V
F
L
G
F
A
Y
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
579
HHSearch
65.28
54%
1
- C3 -
-
4L44
1
KS6B1_HUMAN
A:
[16-345]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
--
V
RN
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
-----------
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
-
D
S
K
F
T
R
---
Q
----
T
-----------------------
S
E
S
-----
A
N
Q
V
F
L
G
F
A
Y
V
A
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Blastp_CBE
65.13
55%
-113
- C3 -
-
3A62
1
KS6B1_HUMAN
A:
[13-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
-----------------------
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
-------------------
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
577
HHSearch
64.67
43%
-28
- C3 -
-
2JDO
2
AKT2_HUMAN
A:
[6-341]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
K
D
-
E
-
V
A
-
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
D
G
-
A
T
-----
M
K
--
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
--------------------------------
M
F
E
D
F
D
Y
I
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Blastp_CBE
64.48
53%
6
- C3 -
-
4L43
1
KS6B1_HUMAN
A:
[10-344]
--------------------------------------------------------------------------------------------------------------------------------------------------------
R
----
G
-
P
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
--------------------
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
F
D
S
K
F
T
R
---
Q
----
T
P
V
-----------------------
S
-----
A
N
Q
V
F
L
G
F
A
Y
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Blastp_CBE
64.31
53%
9
- C3 -
-
4L45
1
KS6B1_HUMAN
A:
[10-344]
--------------------------------------------------------------------------------------------------------------------------------------------------------
R
----
G
-
P
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
--------------------
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
F
D
S
K
F
T
R
---
Q
----
T
P
V
----------------------
E
S
-----
A
N
Q
V
F
L
G
F
E
Y
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Blastp_CBE
63.82
55%
-116
- C3 -
-
3A61
1
KS6B1_HUMAN
A:
[15-299]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-------------------------
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
--------------------------------------------------------
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Blastp_CBE
62.68
53%
13
- C3 -
-
4L46
1
KS6B1_HUMAN
A:
[9-340]
-------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
----
G
-
P
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
D
----------
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
---
E
E
D
V
S
Q
F
D
S
K
F
T
R
---
Q
----
T
P
V
-------------------------------
Q
V
F
L
G
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Blastp_CBE
62.61
55%
-112
- C3 -
-
3A60
1
KS6B1_HUMAN
A:
[13-299]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
------------------
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
----------------------
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Blastp_CBE
62.33
56%
-124
- C3 -
-
4RLO
4
KS6B1_HUMAN
B:
[1-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
----------------------------------------
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--------------------
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Blastp_CBE
60.82
55%
-5
- C3 -
-
3WE4
1
KS6B1_HUMAN
A:
[15-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
--------
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
563
Fugue
60.56
31%
43
- C3 -
-
2ACX
1
GRK6_HUMAN
A:
[14-532]
KARKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERNPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRNLTQNFLSHTGPDLIPEVPR
Q
L
V
T
N
C
T
Q
R
L
E
Q
G
P
C
K
D
L
F
Q
E
L
T
R
L
T
H
E
Y
L
S
V
A
P
F
A
D
Y
L
D
S
I
--
Y
F
N
R
F
L
Q
W
K
W
L
E
R
Q
P
V
T
K
N
T
------
F
R
Q
Y
R
V
L
G
K
G
-
G
F
G
E
V
C
A
C
Q
V
---
R
A
T
G
K
M
Y
A
C
K
K
L
-
E
K
-
K
-
R
I
--
K
--
K
-
R
-
K
G
E
A
-
M
-
A
L
N
-
E
K
Q
I
L
-
E
--
K
V
----
N
---
S
R
-
F
V
V
S
L
A
Y
A
Y
E
T
K
D
A
L
C
L
V
L
T
L
M
N
G
G
D
L
K
F
H
I
Y
H
MG
Q
A
G
F
P
E
A
R
A
V
F
Y
A
A
E
I
C
C
G
L
E
D
L
H
R
-
E
R
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
D
H
G
H
I
R
I
S
D
L
G
-
L
------------------------------
A
V
H
-
V
-
P
E
G
-
Q
T
-----
I
K
--
G
R
V
G
T
V
G
Y
M
A
P
E
V
V
K
-----
N
E
---
R
-----
Y
T
F
S
P
D
W
W
A
L
G
C
L
L
Y
E
M
I
A
G
-
Q
S
P
F
---
Q
---
Q
R
KKKI
K
R
E
E
----
V
E
R
------
L
V
K
--
E
V
--
P
E
--
E
Y
---
S
--
E
R
---
F
S
P
Q
A
R
S
L
C
S
Q
L
L
C
K
D
P
A
E
--
R
L
G
C
R
G
-
G
-
S
A
R
E
-
V
K
E
H
P
L
F
K
K
L
N
---
F
K
R
L
G
A
G
M
L
E
P
P
F
K
P
D
P
Q
A
I
Y
C
E
-
P
T
D
Q
D
F
Y
Q
---
K
----
F
A
T
---
G
S
V
--------------------------------------------------------------------------------------------------------------------------------------------------
P
I
P
W
Q
N
E
M
V
E
T
E
C
F
Q
E
L
N
V
-------------------------------------------------------------------------------------------------------
F
G
L
D
G
S
-------------------------------------------------------------------------------------------------------------------
454
Blastp_CBE
60.40
38%
-20
- C3 -
-
6C0T
3
KGP1_HUMAN
A:
[34-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
------
F
N
I
I
D
T
L
G
V
G
-
G
F
G
R
V
E
L
V
Q
--
L
K
S
E
E
S
K
T
F
A
M
K
I
L
-
K
K
-
R
H
I
V
--
D
--
T
-
R
-
Q
-
Q
E
-
H
-
I
R
S
-
E
K
Q
I
M
-
Q
--
G
A
----
H
---
S
D
-
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
R
D
--
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
-
H
R
G
Y
A
K
L
V
D
F
G
-
F
------------------------------
A
K
K
-
I
-
G
F
G
-
K
K
-----
T
W
--
T
F
C
G
T
P
E
Y
V
A
P
E
I
I
L
-----
N
K
---
G
-----
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
-
S
P
P
F
---
S
---
G
P
----
D
P
M
K
----
T
Y
N
------
I
I
L
--
R
G
ID
M
I
--
E
F
---
P
--
K
K
---
I
A
K
N
A
A
N
L
I
K
K
L
C
R
D
N
P
S
E
--
R
L
G
N
L
K
-
N
-
G
V
K
D
-
I
Q
K
H
K
W
F
E
G
F
N
---
W
E
G
L
R
K
G
T
L
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
------------
F
P
E
---
D
N
D
--
E
--
P
---
P
--
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Blastp_CBE
60.37
55%
-110
- C3 -
-
3A60
1
KS6B1_HUMAN
B:
[13-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
----------------------------------------
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
-------------------
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
132
Blastp_CBE
60.23
39%
-34
- C3 -
-
2UZW
1
KAPCA_BOVIN
E:
[24-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Blastp_CBE
60.16
52%
5
- C3 -
-
4L42
1
KS6B1_HUMAN
A:
[13-344]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
D
G
-
T
V
-----
T
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
------------------------------------------------------------
E
M
F
R
D
F
E
Y
I
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
459
Blastp_CBE
60.07
38%
-26
- C3 -
-
6BDL
1
KGP1_HUMAN
B:
[34-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
------
F
N
I
I
D
T
L
G
V
G
-
G
F
G
R
V
E
L
V
Q
--
L
K
S
E
E
S
K
T
F
A
M
K
I
L
-
K
K
-
R
H
I
V
--
D
--
T
-
R
-
Q
-
Q
E
-
H
-
I
R
S
-
E
K
Q
I
M
-
Q
--
G
A
----
H
---
S
D
-
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
R
D
--
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
-
H
R
G
Y
A
K
L
V
D
F
G
-
F
------------------------------
A
K
K
-
I
-
G
F
G
-
K
K
-----
T
W
--
T
F
C
G
T
P
E
Y
V
A
P
E
I
I
L
-----
N
K
---
G
-----
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
-
S
P
P
F
---
S
---
G
P
----
D
P
M
K
----
T
Y
N
------
I
I
L
--
R
G
ID
M
I
--
E
F
---
P
--
K
K
---
I
A
K
N
A
A
N
L
I
K
K
L
C
R
D
N
P
S
E
--
R
L
G
N
L
K
-
N
-
G
V
K
D
-
I
Q
K
H
K
W
F
E
G
F
N
---
W
E
G
L
R
K
G
T
L
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
------------
F
P
E
---
D
N
D
--
E
--
P
---
P
--
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Blastp_CBE
60.05
54%
4
- C3 -
-
4L3J
1
KS6B1_HUMAN
A:
[14-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
D
G
-
T
V
-----
T
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Blastp_CBE
60.04
54%
4
- C3 -
-
4L3L
1
KS6B1_HUMAN
A:
[14-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
-
H
D
G
-
T
V
-----
T
H
--
T
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
148
Blastp_CBE
59.98
38%
-32
- C3 -
-
2F7X
1
KAPCA_BOVIN
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
460
Blastp_CBE
59.77
38%
-24
- C3 -
-
6BDL
1
KGP1_HUMAN
A:
[34-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
------
F
N
I
I
D
T
L
G
V
G
-
G
F
G
R
V
E
L
V
Q
--
L
K
S
E
E
S
K
T
F
A
M
K
I
L
-
K
K
-
R
H
I
V
--
D
--
T
-
R
-
Q
-
Q
E
-
H
-
I
R
S
-
E
K
Q
I
M
-
Q
--
G
A
----
H
---
S
D
-
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
R
D
--
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
-
H
R
G
Y
A
K
L
V
D
F
G
-
F
------------------------------
A
K
K
-
I
-
G
F
G
-
K
K
-----
T
W
--
T
F
C
G
T
P
E
Y
V
A
P
E
I
I
L
-----
N
K
---
G
-----
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
-
S
P
P
F
---
S
---
G
P
----
D
P
M
K
----
T
Y
N
------
I
I
L
--
R
G
ID
M
I
--
E
F
---
P
--
K
K
---
I
A
K
N
A
A
N
L
I
K
K
L
C
R
D
N
P
S
E
--
R
L
G
N
L
K
-
N
-
G
V
K
D
-
I
Q
K
H
K
W
F
E
G
F
N
---
W
E
G
L
R
K
G
T
L
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
------------
F
P
E
---
D
N
D
--
E
--
P
---
P
--
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
149
Blastp_CBE
59.70
38%
-30
- C3 -
-
2F7E
1
KAPCA_BOVIN
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
146
Blastp_CBE
59.40
38%
-33
- C3 -
-
2OH0
1
KAPCA_BOVIN
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
145
Blastp_CBE
59.39
38%
-34
- C3 -
-
2OJF
1
KAPCA_BOVIN
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
591
HHSearch
59.30
38%
-0
- C3 -
-
5LI9
13
KPCI_HUMAN
A:
[5-343]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
D
------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
D
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
D
I
D
-
W
-
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
-
R
P
G
-
D
T
-----
T
S
--
T
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
-----------------TEDY
L
F
Q
------
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
Q
T
-
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
---
E
----
P
V
Q
---
L
T
P
--
D
--
D
---
D
DI
V
--
R
K
I
-----
D
Q
S
E
F
E
G
F
E
Y
I
N
P
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
133
Blastp_CBE
59.19
39%
-29
- C3 -
-
2UZV
1
KAPCA_BOVIN
A:
[24-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
135
Blastp_CBE
59.15
39%
-31
- C3 -
-
2UZT
1
KAPCA_BOVIN
A:
[24-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134
Blastp_CBE
59.12
39%
-34
- C3 -
-
2UZU
1
KAPCA_BOVIN
E:
[24-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Blastp_CBE
59.01
55%
3
- C3 -
-
3WF7
2
KS6B1_HUMAN
A:
[13-304]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
--------
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
578
HHSearch
58.44
42%
3
- C3 -
-
4RA5
3
KPCT_HUMAN
A:
[3-328]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
E
D
------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
F
K
K
---
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
D
D
-
D
-
V
E
-
C
-
T
M
V
-
E
K
R
V
L
-
S
L-
A
W
----
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
------
V
R
G
D
-
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
E
F
L
N
---
E
----
K
P
R
---
L
S
F
--
A
--
D
---
R
--
A
LI
N
S
M
-----
D
Q
N
M
F
R
N
F
S
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
594
HHSearch
58.30
38%
-24
* C3 *
-
4WB7
1
DNJB1_HUMAN (first)
A:
[93-390]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
K
E
---
T
G
N
H
Y
A
M
K
I
L
-
D
K
-
Q
-
K
V
--
V
--
K
L
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
K
-
G
----
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
E
---
E
----
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
147
Blastp_CBE
58.05
38%
-33
- C3 -
-
2F7Z
1
KAPCA_BOVIN
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
W
--
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
581
HHSearch
57.75
40%
-14
- C3 -
-
3TXO
1
KPCL_HUMAN
A:
[23-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
------
F
E
F
I
R
V
L
G
K
G
-
S
F
G
K
V
M
L
A
R
V
K
E
---
T
G
D
L
Y
A
V
K
V
L
-
K
K
-
D
-
V
I
--
L
--
Q
D
D
-
D
-
V
E
-
C
-
T
M
T
-
E
K
R
I
L
-
S
--
L
A
R---
N
---
H
P
-
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
Q
K
--
S
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
H
E
G
H
C
K
L
A
D
F
G
-
M
------------------------------
C
K
E
G
I
------------------
C
G
T
P
D
Y
I
A
P
E
I
L
Q
-----
E
M
---
L
-----
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
-
H
A
P
F
---
E
---
A
E
----
N
E
D
D
----
L
F
E
------
A
I
L
--
N
D
--
E
V
--
V
Y
---
P
--
T
W
---
L
H
E
D
A
T
G
I
L
K
S
F
M
T
K
N
P
T
M
--
R
L
G
S
L
T
Q
G
-
G
E
H
A
-
I
L
R
H
P
F
F
K
E
I
D
---
W
A
Q
L
N
H
R
Q
I
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
D
P
D
F
I
K
---
E
----
E
P
V
---
L
T
P
--
I
DE
G
---
H
--
L
--
P
M
I
-----
N
Q
D
E
F
R
N
F
E
Y
V
S
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Blastp_CBE
57.73
55%
-62
- C3 -
-
3WF5
1
KS6B1_HUMAN
A:
[15-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
---------------------
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
-
G
T
-----
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115
Blastp_CBE
57.42
42%
11
- C3 -
-
4Q9Z
1
KPCT_HUMAN
A:
[7-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
E
F
L
N
---
E
----
K
P
R
LFA
D
R
A
--
L
--
I
---------
N
S
M
-----
D
Q
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
588
HHSearch
57.39
42%
-14
- C3 -
-
4OTH
1
A:
[10-338]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
E
D
------
F
K
F
L
A
V
L
G
R
G
-
H
F
G
K
V
L
L
S
E
F
R
P
---
S
G
E
L
F
A
I
K
A
L
-
K
K
-
G
-
D
I
--
V
--
A
-
R
D
E
-
V
E
-
S
-
L
M
C
-
E
K
R
I
L
-
A
--
A
V
TSA-
G
---
H
P
-
F
L
V
N
L
F
G
C
F
Q
T
P
E
H
V
C
F
V
M
E
Y
S
A
G
G
D
L
M
L
H
I
H
S
---
D
V
F
S
E
P
R
A
I
F
Y
S
A
C
V
V
L
G
L
Q
F
L
H
E
-
H
K
I
V
Y
R
D
L
K
L
D
N
L
L
L
D
-
T
E
G
Y
V
K
I
A
D
F
G
-
L
------------------------------
C
K
---------------------------------------------------
T
R
A
V
D
W
W
G
L
G
V
L
L
Y
E
M
L
V
G
-
E
S
P
F
---
P
---
G
D
----
D
E
E
E
----
V
F
D
------
S
I
V
--
N
D
--
E
V
--
R
Y
---
P
--
R
F
---
L
S
A
E
A
I
G
I
M
R
R
L
L
R
R
N
P
E
R
--
R
L
G
S
S
E
-
R
-
D
A
E
D
-
V
K
K
Q
P
F
F
R
T
L
G
---
W
E
A
L
L
A
R
R
L
P
P
P
F
V
P
T
L
S
G
R
T
D
V
S
N
F
D
E
E
F
T
G
---
E
----
A
P
T
---
L
S
P
--
P
--
R
DAR
P
--
L
--
T
A
A
-----
E
Q
A
A
F
L
D
F
D
F
V
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
156
Blastp_CBE
57.36
43%
-13
- C3 -
-
4OTH
1
A:
[14-339]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
F
L
A
V
L
G
R
G
-
H
F
G
K
V
L
L
S
E
--
F
R
P
-
S
G
E
L
F
A
I
K
A
L
-
K
K
-
G
-
D
I
--
V
--
A
-
R
-
D
-
E
V
-
E
-
S
L
M
C
E
K
R
I
L
-
A
--
A
V
----
T
SAG
H
P
-
F
L
V
N
L
F
G
C
F
Q
T
P
E
H
V
C
F
V
M
E
Y
S
A
G
G
D
L
M
L
H
I
H
S
--
D
V
-
F
S
E
P
R
A
I
F
Y
S
A
C
V
V
L
G
L
Q
F
L
H
E
-
H
K
I
V
Y
R
D
L
K
L
D
N
L
L
L
D
-
T
E
G
Y
V
K
I
A
D
F
G
-
L
------------------------------
C
K
---------------------------------------------------
T
R
A
V
D
W
W
G
L
G
V
L
L
Y
E
M
L
V
G
-
E
S
P
F
---
P
---
G
D
----
D
E
E
E
----
V
F
D
------
S
I
V
--
N
D
--
E
V
--
R
Y
---
P
--
R
F
---
L
S
A
E
A
I
G
I
M
R
R
L
L
R
R
N
P
E
R
--
R
L
G
S
S
E
-
R
-
D
A
E
D
-
V
K
K
Q
P
F
F
R
T
L
G
---
W
E
A
L
L
A
R
R
L
P
P
P
F
V
P
T
L
S
G
R
T
D
V
S
N
F
D
E
E
F
T
G
---
E
----
A
P
T
---
L
P
P
RD
A
--
R
---
P
--
L
--
T
A
A
-----
E
Q
A
A
F
L
D
F
D
F
V
A
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
123
Blastp_CBE
57.34
37%
-16
- C3 -
-
4DC2
1
KPCI_MOUSE
A:
[49-387]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
Q
D
------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
R
V
V
-
K
K
-
E
-
L
V
--
N
---------
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
-
R
P
G
-
D
T
-----
T
S
--
T
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IVG
S
--------------
N
T
EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
EPV
Q
----
L
P
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Blastp_CBE
57.28
55%
-62
- C3 -
-
3WF6
1
KS6B1_HUMAN
A:
[15-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
---------------------
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
-
G
T
-----
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
564
Fugue
57.11
35%
30
- C3 -
-
4AW2
5
MRCKA_RAT
A:
[1-416]
-------------------------------------------------------------------------------------SGEVRLRQLEQFILDGPA
Q
T
N
G
Q
C
F
S
V
E
T
L
L
D
I
L
I
C
L
Y
D
E
C
N
N
S
P
----
L
R
R
E
K
N
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L
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L
--
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W
A
K
P
F
T
S
K
V
K
-
Q
M
R
L
H
R
E
D
------
F
E
I
L
K
V
I
G
R
G
-
A
F
G
E
V
A
V
V
K
L
---
K
N
A
D
K
V
F
A
M
K
I
L
-
N
K
-
W
-
E
M
--
L
--
K
-
R
A
E
-
T
A
-
C
-
F
R
E
-
E
R
D
V
L
-
V
--
N
G
----
D
---
S
K
-
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F-
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
-
M
N
G
H
I
R
L
A
D
F
G
S
C
------------------------------
L
K
L
M
E
-
D
G
T
-
V
Q
-----
S
S
--
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
-----
A
M
---
E
GGKGR
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
-
E
T
P
F
---
Y
---
A
E
----
S
L
V
E
----
T
Y
G
------
K
I
M
NH
K
E
--
R
F
--
Q
F
---
P
--
T
Q
VTD
V
S
E
N
A
K
D
L
I
R
R
L
I
-
C
S
R
E
H
--
R
L
G
--
Q
-
N
-
G
I
E
D
-
F
K
K
H
P
F
F
S
G
I
D
---
W
D
N
I
--
R
N
C
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
D
------------------------------------
S
G
-----
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
R
S
C
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119
Blastp_CBE
57.05
42%
8
- C3 -
-
5F9E
1
KPCT_HUMAN
A:
[21-342]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
E
F
L
N
---
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----
K
P
R
LFA
D
R
A
--
L
--
I
---------
N
S
M
-----
D
Q
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
587
HHSearch
57.01
36%
-17
- C3 -
-
6ED6
1
ROCK2_HUMAN
A:
[85-413]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
A
E
D
------
Y
D
V
V
K
V
I
G
R
G
-
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
Q
K
V
Y
A
M
K
L
L
-
S
K
-
F
-
E
M
--
I
--
K
R
S
-
D
-
S
A
-
F
-
F
W
E
-
E
R
D
I
M
-
A
--
F
A
----
N
---
S
P
-
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
S
N
--
Y
-
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
-
K
H
G
H
L
K
L
A
D
F
G
-
T
------------------------------
C
M
K
M
D
-
E
T
G
M
V
H
-----
C
D
--
T
A
V
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
----F----
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
-
D
T
P
F
---
Y
---
A
D
----
S
L
V
G
----
T
Y
S
------
K
I
M
--
D
H
--
K
N
SL
C
F
---
P
ED
A
E
---
I
S
K
H
A
K
N
L
I
C
A
F
L
T
D
R
E
V
R
LG
R
N
G
-------
V
E
E
-
I
R
Q
H
P
F
F
K
N
D
Q
---
W
H
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
-----------------
E
T
F
--
P
--
I
---
P
K-
A
--
F
V
G
-----
N
Q
L
P
F
I
G
F
T
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
Blastp_CBE
56.94
43%
-6
- C3 -
-
6CCY
1
AKT1_HUMAN
A:
[1-339]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
S
L
R
V
T
M
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
S
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
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I
M
Q
H
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F
F
A
G
I
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---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
E
E
F
T
A
---
Q
MITI
T
P
-------------------------------
Q
E
M
F
R
D
F
D
Y
I
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
490
Blastp_CBE
56.88
36%
-16
- C3 -
-
4AW2
3
MRCKA_RAT
A:
[76-416]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
I
L
K
V
I
G
R
G
-
A
F
G
E
V
A
V
V
K
---
L
K
N
A
D
K
V
F
A
M
K
I
L
-
N
K
W
E
-
M
L
--
K
--
R
-
A
-
E
-
T
A
-
C
-
F
R
E
-
E
R
D
V
L
-
V
--
N
G
----
D
---
S
K
-
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F-
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
-
M
N
G
H
I
R
L
A
D
F
G
-
S
------------------------------
C
L
K
L
M
E
D
G
T
-
V
Q
-----
S
S
--
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
AMEGG
K
G
---
R
-----
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
-
E
T
P
F
---
Y
---
A
E
----
S
L
V
E
----
T
Y
G
------
K
I
M
NH
K
E
--
R
F
--
Q
F
---
P
--
T
Q
VTD
V
S
E
N
A
K
D
L
I
R
R
L
I
C
S
R
-
E
H
--
R
L
G
Q
---
N
-
G
I
E
D
-
F
K
K
H
P
F
F
S
G
I
D
---
W
D
N
I
--
R
N
C
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
D
------------------------------------
S
G
-----
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
R
S
C
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
155
Blastp_CBE
56.32
43%
-16
- C3 -
-
4OTI
1
A:
[14-339]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
F
L
A
V
L
G
R
G
-
H
F
G
K
V
L
L
S
E
--
F
R
P
-
S
G
E
L
F
A
I
K
A
L
-
K
K
-
G
-
D
I
--
V
--
A
-
R
-
D
-
E
V
-
E
-
S
L
M
C
E
K
R
I
L
-
A
--
A
V
----
T
SAG
H
P
-
F
L
V
N
L
F
G
C
F
Q
T
P
E
H
V
C
F
V
M
E
Y
S
A
G
G
D
L
M
L
H
I
H
S
--
D
V
-
F
S
E
P
R
A
I
F
Y
S
A
C
V
V
L
G
L
Q
F
L
H
E
-
H
K
I
V
Y
R
D
L
K
L
D
N
L
L
L
D
-
T
E
G
Y
V
K
I
A
D
F
G
-
L
-----------------------------------------------------------------------------------
T
R
A
V
D
W
W
G
L
G
V
L
L
Y
E
M
L
V
G
-
E
S
P
F
---
P
---
G
D
----
D
E
E
E
----
V
F
D
------
S
I
V
--
N
D
--
E
V
--
R
Y
---
P
--
R
F
---
L
S
A
E
A
I
G
I
M
R
R
L
L
R
R
N
P
E
R
--
R
L
G
S
S
E
-
R
-
D
A
E
D
-
V
K
K
Q
P
F
F
R
T
L
G
---
W
E
A
L
L
A
R
R
L
P
P
P
F
V
P
T
L
S
G
R
T
D
V
S
N
F
D
E
E
F
T
G
---
E
----
A
P
T
---
L
P
P
RD
A
--
R
---
P
--
L
--
T
A
A
-----
E
Q
A
A
F
L
D
F
D
F
V
A
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114
Blastp_CBE
56.14
42%
-8
- C3 -
-
4Q9Z
1
B:
[7-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
----------------------------------------------
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
Blastp_CBE
56.13
45%
1
- C3 -
-
2JDO
2
AKT2_HUMAN
A:
[6-334]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
Blastp_CBE
56.03
45%
-1
- C3 -
-
2X39
1
AKT2_HUMAN
A:
[6-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
Blastp_CBE
55.90
45%
-1
- C3 -
-
2XH5
1
AKT2_HUMAN
A:
[6-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113
Blastp_CBE
55.86
42%
11
- C3 -
-
4RA5
3
KPCT_HUMAN
A:
[7-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
E
F
L
N
---
E
----
K
P
R
LFA
D
R
A
--
L
--
I
---------
N
S
M
-----
D
Q
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
Blastp_CBE
55.61
43%
4
- C3 -
-
3E87
1
AKT2_HUMAN
A:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--
P
--
D
--------------------------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
Blastp_CBE
55.50
43%
5
- C3 -
-
3E87
1
AKT2_HUMAN
B:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--
P
--
D
--------------------------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111
Blastp_CBE
55.25
40%
-5
- C3 -
-
3TXO
1
KPCL_HUMAN
A:
[23-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
------
F
E
F
I
R
V
L
G
K
G
-
S
F
G
K
V
M
L
A
R
V
---
K
E
T
G
D
L
Y
A
V
K
V
L
-
K
K
-
D
-
V
I
--
L
--
Q
-
D
-
D
-
D
V
-
E
-
C
T
M
T
E
K
R
I
L
-
S
--
L
A
R---
N
---
H
P
-
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
Q
K
--
S
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
H
E
G
H
C
K
L
A
D
F
G
-
M
------------------------------
C
K
E
G
I
------------------
C
G
T
P
D
Y
I
A
P
E
I
L
Q
-----
E
M
---
L
-----
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
-
H
A
P
F
---
E
---
A
E
----
N
E
D
D
----
L
F
E
------
A
I
L
--
N
D
--
E
V
--
V
Y
---
P
--
T
W
---
L
H
E
D
A
T
G
I
L
K
S
F
M
T
K
N
P
T
M
--
R
L
G
S
L
T
-
Q
-
G
G
E
H
A
I
L
R
H
P
F
F
K
E
I
D
---
W
A
Q
L
N
H
R
Q
I
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
D
P
D
F
I
-----------
K
---
E
E
P
--
V
--
L
---
P
--
I
--
D
E
G
HLPMI
N
Q
D
E
F
R
N
F
E
Y
V
S
P
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
471
Blastp_CBE
55.21
37%
2
- C3 -
-
5HE3
1
ARBK1_BOVIN
A:
[162-480]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
------------------------------
T
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
Blastp_CBE
55.04
45%
2
- C3 -
-
2UW9
1
AKT2_HUMAN
A:
[6-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
Blastp_CBE
55.02
45%
0
- C3 -
-
1O6L
1
AKT2_HUMAN
A:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
Blastp_CBE
55.02
43%
5
- C3 -
-
3D0E
1
AKT2_HUMAN
B:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--
P
--
D
---------------
R
----------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
453
Blastp_CBE
54.71
36%
26
- C3 -
-
5N23
1
KAPCA_HUMAN
A:
[9-336]
-----------------------------------------------------------------------------------------------------------------------------------
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
R
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
Q
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
----
K
-
G
R
-----
T
P
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
157
Blastp_CBE
54.79
43%
-9
- C3 -
-
4OTG
1
A:
[14-339]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
F
L
A
V
L
G
R
G
-
H
F
G
K
V
L
L
S
E
--
F
R
P
-
S
G
E
L
F
A
I
K
A
L
-
K
K
-
G
-
D
I
--
V
--
A
-
R
-
D
-
E
V
-
E
-
S
L
M
C
E
K
R
I
L
-
A
--
A
V
----
T
SAG
H
P
-
F
L
V
N
L
F
G
C
F
Q
T
P
E
H
V
C
F
V
M
E
Y
S
A
G
G
D
L
M
L
H
I
H
S
--
D
V
-
F
S
E
P
R
A
I
F
Y
S
A
C
V
V
L
G
L
Q
F
L
H
E
-
H
K
I
V
Y
R
D
L
K
L
D
N
L
L
L
D
-
T
E
G
Y
V
K
I
A
D
F
G
-
L
------------------------------
C
K
E
G
M
-
G
Y
G
-
D
R
-----
T
---
S
F
C
G
T
P
E
F
L
A
P
E
V
L
T
-----
D
T
---
S
-----
Y
T
R
A
V
D
W
W
G
L
G
V
L
L
Y
E
M
L
V
G
-
E
S
P
F
---
P
---
G
D
----
D
E
E
E
----
V
F
D
------
S
I
V
--
N
D
--
E
V
--
R
Y
---
P
--
R
F
---
L
S
A
E
A
I
G
I
M
R
R
L
L
R
R
N
P
E
R
--
R
L
G
S
S
E
-
R
-
D
A
E
D
-
V
K
K
Q
P
F
F
R
T
L
G
---
W
E
A
L
L
A
R
R
L
P
P
P
F
V
P
T
L
S
------------
T
G
---
E
----
A
P
T
---
L
P
P
RD
A
--
R
---
P
--
L
--
T
A
A
-----
E
Q
A
A
F
L
D
F
D
F
V
A
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94
Blastp_CBE
54.76
45%
-1
- C3 -
-
3CQU
1
AKT1_HUMAN
A:
[10-329]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
Blastp_CBE
54.76
43%
6
- C3 -
-
3D0E
1
AKT2_HUMAN
A:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--
P
--
D
---------------
R
----------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
Blastp_CBE
54.71
43%
3
- C3 -
-
3E88
1
AKT2_HUMAN
B:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--------------------------------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Blastp_CBE
54.61
43%
3
- C3 -
-
3E88
1
AKT2_HUMAN
A:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
--
I
---
P
--------------------------------
Q
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Blastp_CBE
54.43
55%
-8
- C3 -
-
3WF8
2
KS6B1_HUMAN
A:
[15-302]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
-
G
T
-----
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
Blastp_CBE
54.32
45%
-1
- C3 -
-
3QKK
1
AKT1_HUMAN
A:
[9-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
Blastp_CBE
54.29
42%
-1
- C3 -
-
4RA5
1
B:
[7-328]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
S
P
F
D
-------------------
P
R
L--
D
R
A
--
L
--
I
---------
N
S
M
-----
D
Q
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
Blastp_CBE
54.27
45%
1
- C3 -
-
2JDR
1
AKT2_HUMAN
A:
[6-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
Blastp_CBE
54.25
45%
1
- C3 -
-
3OW4
1
AKT1_HUMAN
B:
[9-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93
Blastp_CBE
54.15
45%
-5
- C3 -
-
3CQW
1
AKT1_HUMAN
A:
[10-329]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
Blastp_CBE
54.11
45%
1
- C3 -
-
3OW4
1
AKT1_HUMAN
A:
[9-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Blastp_CBE
54.11
55%
-7
- C3 -
-
3WF9
2
KS6B1_HUMAN
A:
[15-302]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
------
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
F
A
M
K
V
L
-
K
K
-
A
-
M
I
VR
N
--
A
-
K
-
D
-
T
A
-
H
-
T
K
A
-
E
R
N
I
L
-
E
--
E
V
----
K
---
H
P
-
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
-
H
Q
G
H
V
K
L
T
D
F
G
-
L
------------------------------
C
K
E
S
I
--
H
D
-
G
T
-----
V
T
--
H
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
-
A
P
P
F
---
T
---
G
E
----
N
R
K
K
----
T
I
D
------
K
I
L
--
K
C
--
K
L
--
N
L
---
P
--
P
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
--
R
L
G
A
G
P
-
G
-
D
A
G
E
-
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
Blastp_CBE
54.10
45%
-6
- C3 -
-
4EKK
1
AKT1_HUMAN
B:
[9-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
461
Blastp_CBE
54.07
37%
6
- C3 -
-
5UVC
1
ARBK1_HUMAN
A:
[200-518]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
G
----------------------------------------------
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
482
Blastp_CBE
54.06
37%
13
- C3 -
-
3V5W
1
ARBK1_HUMAN
A:
[191-516]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
G
E
V
N
A
A
D
A
F
D
---------------------
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
Blastp_CBE
54.02
45%
-5
- C3 -
-
4EKK
1
AKT1_HUMAN
A:
[9-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
472
Blastp_CBE
53.99
37%
10
- C3 -
-
4MK0
1
ARBK1_HUMAN
A:
[162-480]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
G
E
V
N
A
A
D
A
F
---------------------
T
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
118
Blastp_CBE
53.98
42%
-8
- C3 -
-
5F9E
1
B:
[21-341]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
E
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
F
R
P
K
V
K
--------------------------------------------------------
N
M
F
R
N
F
-
F
M
N
P
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
462
Blastp_CBE
53.88
37%
14
- C3 -
-
5UUU
2
ARBK1_HUMAN
A:
[200-518]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
G
E
V
----------------------
E
---
D
T
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
Blastp_CBE
53.84
43%
3
- C3 -
-
3E8D
1
AKT2_HUMAN
B:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
----------------------------------------
R
T
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92
Blastp_CBE
53.76
45%
2
- C3 -
-
3MV5
1
AKT1_HUMAN
A:
[10-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90
Blastp_CBE
53.75
45%
0
- C3 -
-
3OCB
1
AKT1_HUMAN
A:
[9-331]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
Blastp_CBE
53.72
41%
-2
- C3 -
-
1O6K
1
AKT2_HUMAN
A:
[1-334]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
----
S
I
T
---
I
---------------------------------------------
R
T
H
F
P
Q
F
D
Y
S
A
S
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
478
Blastp_CBE
53.60
37%
-0
- C3 -
-
5WG5
1
ARBK1_HUMAN
A:
[191-513]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
-------
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
---
V
N
A
A
D
A
F
--------------------
D
T
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
464
Blastp_CBE
53.59
39%
-103
- C3 -
-
5LOH
2
GWL_HUMAN
A:
[38-316]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
I
V
K
P
I
S
-----
G
K
V
Y
L
G
Q
K
-----
G
G
K
L
Y
A
V
K
V
V
-
K
K
-
A
-
D
M
------------------------
L
-
A
--
L
S
----
K
---
S
P
-
F
I
V
H
L
Y
Y
S
L
Q
S
A
N
N
V
Y
L
V
M
E
Y
L
I
G
G
D
V
K
S
L
L
H
I
--
Y
G
Y
F
D
E
E
M
A
V
K
Y
I
S
E
V
A
L
A
L
D
Y
L
H
R
-
H
G
I
I
H
R
D
L
K
P
D
N
M
L
I
S
-
N
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------
S
K
--------------------
F
C
G
T
P
D
Y
L
A
P
E
L
L
L
-----
G
R
---
A
-----
H
G
P
A
V
D
W
W
A
L
G
V
C
L
F
E
F
L
T
G
-
I
P
P
F
---
N
---
D
E
----
T
P
Q
Q
----
V
F
Q
------
N
I
L
--
K
R
--
D
I
--
P
W
---
P
--
E
G
EEK
L
S
D
N
A
Q
S
A
V
E
I
L
L
T
I
D
D
T
K
--
R
A
-------
G
M
K
E
-
L
K
R
H
P
L
F
S
D
V
D
---
W
E
N
L
Q
H
Q
T
M
--
P
F
I
P
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89
Blastp_CBE
53.52
45%
-1
- C3 -
-
3OCB
1
AKT1_HUMAN
B:
[9-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
Blastp_CBE
53.49
45%
-1
- C3 -
-
3QKL
1
AKT1_HUMAN
A:
[9-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91
Blastp_CBE
53.38
45%
1
- C3 -
-
3MVH
1
AKT1_HUMAN
A:
[10-333]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
------
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
--
K
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
----
M
I
T
---
I
T
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
Blastp_CBE
53.36
43%
3
- C3 -
-
3E8D
1
AKT2_HUMAN
A:
[1-327]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
T
M
N
D
------
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
E
K
A
---
T
G
R
Y
Y
A
M
K
I
L
-
R
K
-
E
-
V
I
--
I
--
A
-
K
-
D
-
E
V
A
H
-
T
V
T
-
E
S
R
V
L
-
Q
--
N
T
----
R
---
H
P
-
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
S
-
D
-
G
A
-----
T
M
--
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
R
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
P
-
S
-
D
A
K
E
-
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
---
Q
-----------
S
I
--
T
------------------------------------------
H
F
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
585
HHSearch
52.52
42%
-9
- C3 -
-
1XJD
1
A:
[16-335]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
D
------
F
I
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
F
K
K
---
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
D
D
-
D
-
V
E
-
C
-
T
M
V
-
E
K
R
V
L
-
S
L-
A
W
----
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
N
--
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
------
V
R
G
D
-
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
--------------------------------------------------------------
Q
N
M
F
R
N
F
S
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
200
Blastp_CBE
52.28
41%
-5
- C3 -
-
4CRS
1
A:
[14-338]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
C
C
A
V
L
L
R
G
-
H
F
G
K
V
L
L
A
E
Y
---
K
N
T
N
E
M
F
A
I
K
A
L
-
K
K
-
G
-
D
I
--
V
--
A
-
R
-
D
-
E
V
-
D
-
S
L
M
C
E
K
R
I
F
-
E
--
T
V
----
N
SVR
H
P
-
F
L
V
N
L
F
A
C
F
Q
T
K
E
H
V
C
F
V
M
E
Y
A
A
G
G
D
L
M
M
H
I
H
T
--
D
V
F
S
-
E
P
R
A
V
F
Y
A
A
C
V
V
L
G
L
Q
Y
L
H
E
-
H
K
I
V
Y
R
D
L
K
L
D
N
L
L
L
D
-
T
E
G
F
V
K
I
A
D
F
G
-
L
------------------------------
C
K
E
G
M
-
G
Y
G
-
D
R
-----
T
---
S
F
C
G
T
P
E
F
L
A
P
E
V
L
T
-----
E
T
---
S
-----
Y
T
R
A
V
D
W
W
G
L
G
V
L
I
Y
E
M
L
V
G
-
E
S
P
F
---
P
---
G
D
----
D
E
E
E
----
V
F
D
------
S
I
V
--
N
D
--
E
V
--
R
Y
---
P
--
R
F
---
L
S
T
E
A
I
S
I
M
R
R
L
L
R
R
N
P
E
R
--
R
L
G
A
S
E
-
K
-
D
A
E
D
-
V
K
K
H
P
F
F
R
L
I
D
---
W
S
A
L
M
D
K
K
V
K
P
P
F
I
P
T
I
R
G
R
E
D
V
S
N
F
D
D
E
F
T
S
---
E
----
A
P
I
---
L
P
P
--
R
--
E
---
P
--
R
IL------------
F
R
D
F
D
Y
I
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
151
Blastp_CBE
52.19
38%
-6
- C3 -
-
5LI1
2
KPCI_HUMAN
A:
[12-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IV------------------EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
----
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
EPV
Q
----
L
P
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
239
Blastp_CBE
52.13
39%
-17
- C3 -
-
1SMH
6
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
E
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
L
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
170
Blastp_CBE
52.03
39%
-17
- C3 -
-
5MHI
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
164
Blastp_CBE
52.03
39%
-18
- C3 -
-
5N7U
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
Blastp_CBE
51.83
44%
-5
- C3 -
-
3PFQ
1
KPCB_RAT
A:
[341-643]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
------
F
N
F
L
M
V
L
G
K
G
-
S
F
G
K
V
M
L
S
E
---
R
K
G
T
D
E
L
Y
A
V
K
I
L
-
K
K
-
D
-
V
V
--
I
--
Q
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
A
--
L
P
----
G
---
K
P
P
F
L
T
Q
L
H
S
C
F
Q
T
M
D
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Y
H
I
Q
Q
--
V
G
R
F
K
E
P
H
A
V
F
Y
A
A
E
I
A
I
G
L
F
F
L
Q
S
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
M
L
D
-
S
E
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
I
--
W
D
-
G
V
-----
T
T
--
K
F
C
G
T
P
D
Y
I
A
P
E
I
I
A
-----
Y
Q
---
P
-----
Y
G
K
S
V
D
W
W
A
F
G
V
L
L
Y
E
M
L
A
G
-
Q
A
P
F
---
E
---
G
E
----
D
E
D
E
----
L
F
Q
------
S
I
M
--
E
H
--
N
V
--
A
Y
---
P
--
K
S
---
M
S
K
E
A
V
A
I
C
K
G
L
M
T
K
H
P
G
K
--
R
L
G
C
G
P
-
E
-
G
E
R
D
-
I
K
E
H
A
F
F
R
Y
I
D
---
W
E
K
L
E
R
K
E
I
Q
P
P
Y
K
P
K
-
A
S
G
R
N
A
E
N
F
D
R
F
F
T
----
R
----
H
P
------
P
--
V
--
L
---
P
--
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
360
Blastp_CBE
51.82
39%
-17
- C3 -
-
5N39
5
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
481
Blastp_CBE
51.81
37%
11
- C3 -
-
4PNK
1
ARBK1_HUMAN
A:
[191-509]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
V
H
R
I
I
G
R
G
-
G
F
G
E
V
Y
G
C
R
K
A
---
D
T
G
K
M
Y
A
M
K
C
L
-
D
K
-
K
-
R
I
--
K
--
M
-
K
-
Q
-
G
E
-
T
-
L
A
L
-
N
E
R
I
M
-
L
--
S
L
VSTG
D
---
C
P
-
F
I
V
C
M
S
Y
A
F
H
T
P
D
K
L
S
F
I
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
--
H
G
V
F
S
E
A
D
M
R
F
Y
A
A
E
I
I
L
G
L
E
H
M
H
N
-
R
F
V
V
Y
R
D
L
K
P
A
N
I
L
L
D
-
E
H
G
H
V
R
I
S
D
L
G
-
L
------------------------------
A
C
D
F
---
S
K
-
K
K
-----
P
H
--
A
S
V
G
T
H
G
Y
M
A
P
E
V
L
Q
-----
K
G
V--
A
-----
Y
D
S
S
A
D
W
F
S
L
G
C
M
L
F
K
L
L
R
G
-
H
S
P
F
RQH
K
---
T
K
----
D
K
H
E
----
I
D
R
------
M
T
L
--
T
M
--
A
V
--
E
L
---
P
--
D
S
---
F
S
P
E
L
R
S
L
L
E
G
L
L
Q
R
D
V
N
R
--
R
L
G
C
L
G
-
R
-
G
A
Q
E
-
V
K
E
S
P
F
F
R
S
L
D
---
W
Q
M
V
F
L
Q
K
Y
P
P
P
L
I
P
P
R
-
E
V
N
A
-------------------------
T
K
--
G
--
I
---
K
--
L
--
L
D
S
-----
D
Q
E
L
Y
R
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
567
Fugue
51.75
33%
15
- C3 -
-
1CDK
2
KAPCA_PIG
A:
[8-350]
-------------------------------------------------------------------------------------------------------------------------
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
A
K
E
D
F
L
K
K
W
E
--
N
P
A
Q
N
T
A
-------
H
--
L
D
Q
------
F
E
R
I
K
T
L
G
T
-G
S
F
G
R
V
M
L
V
K
H
--
K
E
T
G
-
N
H
F
A
M
K
I
L
-
D
K
-
Q
-
K
V
--
V
K-
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
AV------
N
---
F
P
-
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
I--
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q-
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
--
K
---
G
-------
R
TW
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
-KGY-------
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y-
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
S--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
---TTD
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
E
---
E
IRV-
S
I
----------------------
N
E
K
-----
C
G
K
E
F
S
E
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
173
Blastp_CBE
51.72
39%
-18
- C3 -
-
5M6Y
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
359
Blastp_CBE
51.68
39%
-17
- C3 -
-
5N3A
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
362
Blastp_CBE
51.67
39%
-17
- C3 -
-
5N36
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
376
Blastp_CBE
51.55
39%
-19
- C3 -
-
4C38
4
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
Y
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
361
Blastp_CBE
51.59
39%
-19
- C3 -
-
5N37
6
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
238
Blastp_CBE
51.56
39%
-13
- C3 -
-
1XHA
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
E
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
L
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
Blastp_CBE
51.55
43%
-3
- C3 -
-
4RA4
1
KPCA_HUMAN
A:
[20-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
------
F
N
F
L
M
V
L
G
K
G
-
S
F
G
K
V
M
L
A
---
D
R
K
G
T
E
E
L
Y
A
I
K
I
L
-
K
K
-
D
-
V
V
--
I
--
Q
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
A
--
L
L
----
D
---
K
P
P
F
L
T
Q
L
H
S
C
F
Q
T
V
D
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Y
H
I
Q
Q
--
V
G
K
F
K
E
P
Q
A
V
F
Y
A
A
E
I
S
I
G
L
F
F
L
H
K
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
M
L
D
-
S
E
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
H
M
--
M
D
-
G
V
-----
T
T
--
R
F
C
G
T
P
D
Y
I
A
P
E
I
I
A
-----
Y
Q
---
P
-----
Y
G
K
S
V
D
W
W
A
Y
G
V
L
L
Y
E
M
L
A
G
-
Q
P
P
F
---
D
---
G
E
----
D
E
D
E
----
L
F
Q
------
S
I
M
--
E
H
--
N
V
--
S
Y
---
P
--
K
S
---
L
S
K
E
A
V
S
I
C
K
G
L
M
T
K
H
P
A
K
--
R
L
G
C
G
P
-
E
-
G
E
R
D
-
V
R
E
H
A
F
F
R
R
I
D
---
W
E
K
L
E
N
R
E
I
Q
P
P
F
K
P
K
V
S
G
K
G
A
E
P
N
F
D
K
F
F
T
-----------
R
---
G
Q
P
--
V
--
L
---
P
--
P
--
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
416
Blastp_CBE
51.46
39%
-15
- C3 -
-
3KKV
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
229
Blastp_CBE
51.50
39%
-16
- C3 -
-
3IDC
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
273
Blastp_CBE
51.49
39%
-16
- C3 -
-
4UJA
2
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
363
Blastp_CBE
51.47
39%
-15
- C3 -
-
5N33
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
236
Blastp_CBE
51.46
39%
-12
- C3 -
-
1FMO
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
367
Blastp_CBE
51.45
39%
-15
- C3 -
-
5N1L
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
313
Blastp_CBE
51.44
39%
-14
- C3 -
-
6I2H
1
?
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
364
Blastp_CBE
51.37
39%
-23
- C3 -
-
5N1O
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
-
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
366
Blastp_CBE
51.34
39%
-17
- C3 -
-
5N1M
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
334
Blastp_CBE
51.33
39%
-15
- C3 -
-
5OTG
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
392
Blastp_CBE
51.27
39%
-19
- C3 -
-
4DH1
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
441
Blastp_CBE
51.22
38%
-14
- C3 -
-
2UW8
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
153
Blastp_CBE
51.27
39%
-18
- C3 -
-
1YDS
1
KAPCA_BOVIN
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
284
Blastp_CBE
51.22
39%
-18
- C3 -
-
3L9L
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
159
Blastp_CBE
51.21
39%
-14
- C3 -
-
4YXR
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
447
Blastp_CBE
51.12
38%
-12
- C3 -
-
2UVY
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
168
Blastp_CBE
51.19
39%
-13
- C3 -
-
5N1E
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
162
Blastp_CBE
51.19
39%
-14
- C3 -
-
1XH9
4
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
E
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
L
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
268
Blastp_CBE
51.14
39%
-18
- C3 -
-
5UZK
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
304
Blastp_CBE
51.12
38%
-11
- C3 -
-
2UW7
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
463
Blastp_CBE
51.02
39%
-100
- C3 -
-
5LOH
3
GWL_HUMAN
B:
[38-316]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
I
V
K
P
I
S
R
G
-
A
F
G
K
V
Y
L
G
Q
K
-----
G
G
K
L
Y
A
V
K
V
V
-
K
K
-
A
-
D
M
--
I
--
N
-
K
------------------
A
--
L
S
----
K
---
S
P
-
F
I
V
H
L
Y
Y
S
L
Q
S
A
N
N
V
Y
L
V
M
E
Y
L
I
G
G
D
V
K
S
L
L
H
I
--
Y
G
Y
F
D
E
E
M
A
V
K
Y
I
S
E
V
A
L
A
L
D
Y
L
H
R
-
H
G
I
I
H
R
D
L
K
P
D
N
M
L
I
S
-
N
E
G
H
I
K
L
T
D
F
G
-
L
------------------------------------------------------
G
T
P
D
Y
L
A
P
E
L
L
L
-----
G
R
---
A
-----
H
G
P
A
V
D
W
W
A
L
G
V
C
L
F
E
F
L
T
G
-
I
P
P
F
---
N
---
D
E
----
T
P
Q
Q
----
V
F
Q
------
N
I
L
--
K
R
--
D
I
--
P
W
---
P
--
E
G
EEK
L
S
D
N
A
Q
S
A
V
E
I
L
L
T
I
D
D
T
K
--
R
A
-------
G
M
K
E
-
L
K
R
H
P
L
F
S
D
V
D
---
W
E
N
L
Q
H
Q
T
M
--
P
F
I
P
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
377
Blastp_CBE
51.09
39%
-19
- C3 -
-
4C37
2
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
Y
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
179
Blastp_CBE
51.08
39%
-17
- C3 -
-
5LCU
5
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
356
Blastp_CBE
51.06
39%
-17
- C3 -
-
5N3D
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
180
Blastp_CBE
51.04
39%
-17
- C3 -
-
5LCT
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
246
Blastp_CBE
51.02
39%
-15
- C3 -
-
1XH8
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
336
Blastp_CBE
50.97
39%
-11
- C3 -
-
5OL3
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
445
Blastp_CBE
50.92
38%
-11
- C3 -
-
2UW0
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
303
Blastp_CBE
51.00
38%
-10
- C3 -
-
4AXA
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
400
Blastp_CBE
50.92
39%
-14
- C3 -
-
4XW5
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
166
Blastp_CBE
50.97
39%
-17
- C3 -
-
5N32
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
-
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
165
Blastp_CBE
50.92
39%
-16
- C3 -
-
5N7P
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
171
Blastp_CBE
50.89
39%
-17
- C3 -
-
5M75
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
174
Blastp_CBE
50.88
39%
-17
- C3 -
-
5M6V
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
340
Blastp_CBE
50.87
39%
-18
- C3 -
-
5NTJ
2
KAPCA_CRIGR
A:
[41-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
355
Blastp_CBE
50.86
39%
-18
- C3 -
-
5N3E
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
465
Blastp_CBE
50.76
38%
14
- C3 -
-
6BXI
1
STK38_HUMAN
B:
[8-330]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
S
L
K
V
I
G
R
G
-
A
F
G
E
V
R
L
V
Q
K
---
K
D
T
G
H
V
Y
A
M
K
I
L
-
R
K
-
A
-
D
M
--
L
--
E
-
K
-
E
-
Q
V
G
H
-
I
R
A
-
E
R
D
I
L
-
V
--
E
A
----
D
---
S
L
-
W
V
V
K
M
F
Y
S
F
Q
D
K
L
N
L
Y
L
I
M
E
F
L
P
G
G
D
M
M
T
L
L
M
K
--
K
D
T
L
T
E
E
E
T
Q
F
Y
I
A
E
T
V
L
A
I
D
S
I
H
Q
-
L
G
F
I
H
R
D
I
K
P
D
N
L
L
L
D
-
S
K
G
H
V
K
L
S
D
F
G
-
L
CTGLKKAHRTEFYRNLNHSLPSDFTFQNMN
S
K
R
K
A
-
E
T
W
-
K
R
NRRQL
A
F
--
S
T
V
G
T
P
D
Y
I
A
P
E
V
F
M
-----
Q
T
---
G
-----
Y
N
K
L
C
D
W
W
S
L
G
V
I
M
Y
E
M
L
I
G
-
Y
P
P
F
---
C
---
S
E
----
T
P
Q
E
----
T
Y
K
------
K
V
M
--
N
W
--
K
E
--
T
L
TFP
P
--
E
V
---
P
I
S
E
K
A
K
D
L
I
L
R
F
C
C
E
W
E
H
--
R
I
G
A
---
P
-
G
V
E
E
-
I
K
S
N
S
F
F
E
G
V
D
---
W
E
H
I
--
R
E
R
P
A
A
I
S
I
E
I
K
S
I
D
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
411
Blastp_CBE
50.78
39%
-13
- C3 -
-
4IAC
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
351
Blastp_CBE
50.82
39%
-13
- C3 -
-
5N3I
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
321
Blastp_CBE
50.78
39%
-15
- C3 -
-
6ERT
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
444
Blastp_CBE
50.81
38%
-13
- C3 -
-
2UW3
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
252
Blastp_CBE
50.79
39%
-17
- C3 -
-
4IE9
2
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
308
Blastp_CBE
50.78
38%
-12
- C3 -
-
2JDT
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
249
Blastp_CBE
50.76
39%
-17
- C3 -
-
1SVH
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
295
Blastp_CBE
50.71
39%
-13
- C3 -
-
3L9M
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
178
Blastp_CBE
50.73
39%
-13
- C3 -
-
5M0B
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
275
Blastp_CBE
50.72
39%
-15
- C3 -
-
4UJ2
2
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
143
Blastp_CBE
50.71
40%
-22
- C3 -
-
3A8W
1
KPCI_HUMAN
A:
[11-315]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
---------
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
I-------------------EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
152
Blastp_CBE
50.68
39%
-14
- C3 -
-
1YDT
1
KAPCA_BOVIN
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
240
Blastp_CBE
50.66
39%
-11
- C3 -
-
2ERZ
1
KAPCA_MOUSE
E:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
177
Blastp_CBE
50.67
39%
-17
- C3 -
-
5M0C
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
358
Blastp_CBE
50.62
39%
-16
- C3 -
-
5N3B
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129
Blastp_CBE
50.66
38%
-3
- C3 -
-
5LI9
13
KPCI_HUMAN
A:
[8-343]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
--------------------EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
EPV
Q
----
L
P
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
337
Blastp_CBE
50.62
39%
-16
- C3 -
-
5OK3
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
169
Blastp_CBE
50.65
39%
-17
- C3 -
-
5N1D
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
375
Blastp_CBE
50.64
39%
-12
- C3 -
-
6EM7
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
225
Blastp_CBE
50.61
39%
-14
- C3 -
-
4HPT
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
172
Blastp_CBE
50.61
39%
-16
- C3 -
-
5M71
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
163
Blastp_CBE
50.61
39%
-15
- C3 -
-
2GU8
1
KAPCA_HUMAN
A:
[25-315]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
E
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
160
Blastp_CBE
50.61
39%
-8
- C3 -
-
3DNE
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
422
Blastp_CBE
50.53
39%
-20
- C3 -
-
3X2U
1
KAPCA_MOUSE
A:
[45-335]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
282
Blastp_CBE
50.55
39%
-15
- C3 -
-
3OOG
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
183
Blastp_CBE
50.57
39%
-16
- C3 -
-
5LCP
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
347
Blastp_CBE
50.53
39%
-13
- C3 -
-
5N3M
6
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
402
Blastp_CBE
50.56
39%
-13
- C3 -
-
4IB3
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
350
Blastp_CBE
50.51
39%
-12
- C3 -
-
5N3J
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
248
Blastp_CBE
50.55
39%
-20
- C3 -
-
1XH5
3
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
446
Blastp_CBE
50.46
38%
-9
- C3 -
-
2UVZ
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
154
Blastp_CBE
50.53
39%
-14
- C3 -
-
1YDR
1
KAPCA_BOVIN
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
443
Blastp_CBE
50.43
38%
-10
- C3 -
-
2UW5
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
442
Blastp_CBE
50.43
38%
-11
- C3 -
-
2UW6
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
325
Blastp_CBE
50.51
39%
-14
- C3 -
-
6EMA
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
266
Blastp_CBE
50.50
39%
-9
- C3 -
-
4Z83
2
KAPCA_BOVIN
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
369
Blastp_CBE
50.49
39%
-13
- C3 -
-
5N1G
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
466
Blastp_CBE
50.48
38%
17
- C3 -
-
6BXI
1
STK38_HUMAN
A:
[8-330]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
S
L
K
V
I
G
R
G
-
A
F
G
E
V
R
L
V
Q
K
---
K
D
T
G
H
V
Y
A
M
K
I
L
-
R
K
-
A
-
D
M
--
L
--
E
-
K
-
E
-
Q
V
G
H
-
I
R
A
-
E
R
D
I
L
-
V
--
E
A
----
D
---
S
L
-
W
V
V
K
M
F
Y
S
F
Q
D
K
L
N
L
Y
L
I
M
E
F
L
P
G
G
D
M
M
T
L
L
M
K
--
K
D
T
L
T
E
E
E
T
Q
F
Y
I
A
E
T
V
L
A
I
D
S
I
H
Q
-
L
G
F
I
H
R
D
I
K
P
D
N
L
L
L
D
-
S
K
G
H
V
K
L
S
D
F
G
-
L
CTGLKKAHRTEFYRNLNHSLPSDFTFQNMN
S
K
R
K
A
-
E
T
W
-
K
R
NRRQL
A
F
--
S
T
V
G
T
P
D
Y
I
A
P
E
V
F
M
-----
Q
T
---
G
-----
Y
N
K
L
C
D
W
W
S
L
G
V
I
M
Y
E
M
L
I
G
-
Y
P
P
F
---
C
---
S
E
----
T
P
Q
E
----
T
Y
K
------
K
V
M
--
N
W
--
K
E
--
T
L
TFP
P
--
E
V
---
P
I
S
E
K
A
K
D
L
I
L
R
F
C
C
E
W
E
H
--
R
I
G
A
---
P
-
G
V
E
E
-
I
K
S
N
S
F
F
E
G
V
D
---
W
E
H
I
--
R
E
R
P
A
A
I
S
I
E
I
K
S
I
D
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
328
Blastp_CBE
50.47
39%
-12
- C3 -
-
6EH3
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
335
Blastp_CBE
50.46
39%
-16
- C3 -
-
5OT3
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
294
Blastp_CBE
50.44
39%
-13
- C3 -
-
3L9M
1
KAPCA_HUMAN
B:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
324
Blastp_CBE
50.43
39%
-17
- C3 -
-
6EMB
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
181
Blastp_CBE
50.42
39%
-17
- C3 -
-
5LCR
6
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
312
Blastp_CBE
50.41
39%
-16
- C3 -
-
5NW8
2
KAPCA_CRIGR
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
430
Blastp_CBE
50.24
39%
-19
- C3 -
-
3ZO1
7
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
309
Blastp_CBE
50.39
38%
-14
- C3 -
-
3QAL
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
A
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
395
Blastp_CBE
50.31
39%
-15
- C3 -
-
2QCS
5
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
417
Blastp_CBE
50.28
39%
-15
- C3 -
-
3BWJ
2
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
244
Blastp_CBE
50.35
39%
-14
- C3 -
-
4IJ9
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
405
Blastp_CBE
50.28
39%
-18
- C3 -
-
4IAZ
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
409
Blastp_CBE
50.34
39%
-17
- C3 -
-
4IAF
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
283
Blastp_CBE
50.33
39%
-15
- C3 -
-
3L9L
1
KAPCA_HUMAN
B:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
318
Blastp_CBE
50.30
39%
-13
- C3 -
-
6ESA
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
317
Blastp_CBE
50.30
39%
-18
- C3 -
-
6I2A
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
391
Blastp_CBE
50.27
39%
-14
- C3 -
-
4DH3
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
257
Blastp_CBE
50.32
39%
-16
- C3 -
-
2C1A
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
370
Blastp_CBE
50.27
39%
-14
- C3 -
-
5N1F
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
306
Blastp_CBE
50.31
38%
-12
- C3 -
-
2UVX
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
381
Blastp_CBE
50.20
39%
-13
- C3 -
-
4X6R
4
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
182
Blastp_CBE
50.30
39%
-15
- C3 -
-
5LCQ
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
301
Blastp_CBE
50.28
38%
-13
- C3 -
-
1Q24
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
278
Blastp_CBE
50.26
39%
-16
- C3 -
-
3P0M
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
276
Blastp_CBE
50.26
39%
-16
- C3 -
-
4UJ1
2
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
368
Blastp_CBE
50.27
39%
-14
- C3 -
-
5N1H
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
427
Blastp_CBE
50.19
39%
-15
- C3 -
-
4WB5
1
KAPCA_HUMAN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
247
Blastp_CBE
50.26
39%
-14
- C3 -
-
1XH6
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
341
Blastp_CBE
50.25
39%
-13
- C3 -
-
5N3T
5
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
414
Blastp_CBE
50.10
39%
-14
- C3 -
-
4O21
1
KAPCA_MOUSE
A:
[30-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
175
Blastp_CBE
50.24
39%
-15
- C3 -
-
5M0U
10
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
-----
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
406
Blastp_CBE
50.17
39%
-13
- C3 -
-
4IAY
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
437
Blastp_CBE
50.22
38%
-9
- C3 -
-
2VO6
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
332
Blastp_CBE
50.17
39%
-12
- C3 -
-
5OUC
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
357
Blastp_CBE
50.16
39%
-17
- C3 -
-
5N3C
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
280
Blastp_CBE
50.20
39%
-16
- C3 -
-
3OWP
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
385
Blastp_CBE
50.14
39%
-15
- C3 -
-
5JR7
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
383
Blastp_CBE
50.19
39%
-16
- C3 -
-
4DFX
5
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
260
Blastp_CBE
50.16
37%
12
- C3 -
-
5BX6
4
KAPCA_HUMAN
A:
[6-329]
--------------------------------------------------------------------------------------------------------------------------------
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
232
Blastp_CBE
50.17
39%
-16
- C3 -
-
1REK
2
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
352
Blastp_CBE
50.12
39%
-11
- C3 -
-
5N3H
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
253
Blastp_CBE
50.16
39%
-14
- C3 -
-
3ZO4
4
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
338
Blastp_CBE
50.15
39%
-15
- C3 -
-
5O5M
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
310
Blastp_CBE
50.14
38%
-14
- C3 -
-
1RDQ
3
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
A
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
307
Blastp_CBE
50.13
38%
-14
- C3 -
-
2JDV
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
353
Blastp_CBE
50.08
39%
-13
- C3 -
-
5N3G
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
326
Blastp_CBE
50.12
39%
-15
- C3 -
-
6EM6
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
176
Blastp_CBE
50.11
39%
-12
- C3 -
-
5M0L
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
339
Blastp_CBE
50.10
39%
-12
- C3 -
-
5O0E
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
419
Blastp_CBE
50.09
39%
-16
- C3 -
-
1Q8W
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
286
Blastp_CBE
50.08
39%
-11
- C3 -
-
4Z84
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
371
Blastp_CBE
50.03
39%
-14
- C3 -
-
5N3N
4
KAPCA_CRIGR
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
408
Blastp_CBE
50.06
39%
-13
- C3 -
-
4IAI
2
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
237
Blastp_CBE
50.05
39%
-13
- C3 -
-
1ATP
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
344
Blastp_CBE
50.04
39%
-13
- C3 -
-
5N3Q
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
161
Blastp_CBE
50.03
39%
-16
- C3 -
-
3DND
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
401
Blastp_CBE
49.96
39%
-13
- C3 -
-
4XW4
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
434
Blastp_CBE
50.02
39%
-14
- C3 -
-
4WB8
2
KAPCA_HUMAN
A:
[25-315]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
373
Blastp_CBE
50.01
37%
8
- C3 -
-
4C35
2
KAPCA_BOVIN
A:
[11-329]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
Y
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
330
Blastp_CBE
49.94
39%
-13
- C3 -
-
6EGW
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
---
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
-
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
227
Blastp_CBE
49.96
39%
-15
- C3 -
-
3OW3
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
424
Blastp_CBE
49.89
39%
-10
- C3 -
-
4DG3
1
KAPCA_MOUSE
E:
[59-349]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
158
Blastp_CBE
49.96
39%
-17
- C3 -
-
4YXS
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
256
Blastp_CBE
49.94
39%
-15
- C3 -
-
2C1B
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
420
Blastp_CBE
49.95
39%
-15
- C3 -
-
3X2W
1
KAPCA_MOUSE
A:
[45-335]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
390
Blastp_CBE
49.89
39%
-14
- C3 -
-
4DH5
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
234
Blastp_CBE
49.94
39%
-12
- C3 -
-
1RE8
2
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
287
Blastp_CBE
49.93
39%
-9
- C3 -
-
6C0U
4
KAPCA_HUMAN
A:
[42-332]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
398
Blastp_CBE
49.80
39%
-16
- C3 -
-
6E21
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
418
Blastp_CBE
49.92
39%
-16
- C3 -
-
1XH4
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
440
Blastp_CBE
49.91
38%
-11
- C3 -
-
2VNW
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
439
Blastp_CBE
49.82
38%
-7
- C3 -
-
2VNY
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
394
Blastp_CBE
49.90
39%
-13
- C3 -
-
4DG0
2
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
322
Blastp_CBE
49.86
39%
-15
- C3 -
-
6ERS
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
---
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
389
Blastp_CBE
49.89
39%
-14
- C3 -
-
4DH7
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
251
Blastp_CBE
49.88
39%
-19
- C3 -
-
6E99
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
217
Blastp_CBE
49.87
37%
12
- C3 -
-
1Q8U
3
KAPCA_BOVIN
A:
[7-328]
----------------------------------------------------------------------------------------------------------------------------------
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
399
Blastp_CBE
49.80
39%
-14
- C3 -
-
4XW6
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
315
Blastp_CBE
49.86
39%
-15
- C3 -
-
6I2C
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
---
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
431
Blastp_CBE
49.77
39%
-19
- C3 -
-
2JDS
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
281
Blastp_CBE
49.83
39%
-15
- C3 -
-
3OVV
2
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
305
Blastp_CBE
49.80
38%
-7
- C3 -
-
2UW4
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
-
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
319
Blastp_CBE
49.79
39%
-14
- C3 -
-
6ERW
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
----
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
348
Blastp_CBE
49.77
39%
-12
- C3 -
-
5N3L
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
Blastp_CBE
49.80
45%
9
- C3 -
-
2R5T
1
SGK1_HUMAN
A:
[35-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
P
S
D
------
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
H
K
A
E
E
V
---
F
Y
A
V
K
V
L
Q
K
K
-
A
-
I
L
-----------------------
V
L
L
K
--
N
V
----
K
---
H
P
-
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
S
Q
G
H
I
V
L
T
D
F
G
-
L
------------------------------
C
K
E
N
I
-
E
H
N
-
S
T
-----
T
S
--
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
-
L
P
P
F
---
Y
---
S
R
----
N
T
A
E
----
M
Y
D
------
N
I
L
--
N
K
--
P
L
--
Q
L
---
K
--
P
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
--
R
L
G
A
K
--
D
-
D
F
M
E
-
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
388
Blastp_CBE
49.74
39%
-15
- C3 -
-
4DH8
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
167
Blastp_CBE
49.79
39%
-15
- C3 -
-
5N1K
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
-
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
423
Blastp_CBE
49.78
39%
-16
- C3 -
-
3PVB
1
KAPCA_MOUSE
A:
[33-323]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
128
Blastp_CBE
49.77
38%
-9
- C3 -
-
3ZH8
3
KPCI_HUMAN
A:
[7-343]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IVG----------------
T
EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
--------
F
T
N
----------
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
231
Blastp_CBE
49.76
39%
-14
- C3 -
-
3FJQ
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
404
Blastp_CBE
49.75
39%
-12
- C3 -
-
4IB0
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
230
Blastp_CBE
49.74
39%
-12
- C3 -
-
3IDB
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
279
Blastp_CBE
49.72
39%
-12
- C3 -
-
3OXT
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
195
Blastp_CBE
49.72
39%
-17
- C3 -
-
4NTT
1
KAPCA_MOUSE
B:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
285
Blastp_CBE
49.68
39%
-8
- C3 -
-
3AGM
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
452
Blastp_CBE
49.64
38%
-13
- C3 -
-
6FRX
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
R
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
Q
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
-----
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
345
Blastp_CBE
49.63
39%
-10
- C3 -
-
5N3P
4
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
220
Blastp_CBE
49.62
39%
-12
- C3 -
-
6MM7
9
KAPCA_MOUSE
D:
[27-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
218
Blastp_CBE
49.62
37%
12
- C3 -
-
1Q8T
1
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
349
Blastp_CBE
49.55
39%
-10
- C3 -
-
5N3K
5
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
342
Blastp_CBE
49.59
39%
-10
- C3 -
-
5N3S
5
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
435
Blastp_CBE
49.50
38%
-16
- C3 -
-
3NX8
3
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
-
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
302
Blastp_CBE
49.55
38%
-13
- C3 -
-
3QAM
1
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
A
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
421
Blastp_CBE
49.57
39%
-14
- C3 -
-
3X2V
1
KAPCA_MOUSE
A:
[45-335]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
215
Blastp_CBE
49.55
37%
9
- C3 -
-
1SVE
2
KAPCA_BOVIN
A:
[7-328]
----------------------------------------------------------------------------------------------------------------------------------
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
354
Blastp_CBE
49.54
39%
-16
- C3 -
-
5N3F
3
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
--
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
---
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
397
Blastp_CBE
49.46
39%
-13
- C3 -
-
1L3R
3
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
387
Blastp_CBE
49.51
39%
-16
- C3 -
-
4HPU
2
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
127
Blastp_CBE
49.50
38%
-9
- C3 -
-
3ZH8
5
KPCI_HUMAN
B:
[7-342]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IVG----------------
T
EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
--------
F
T
N
----------
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
142
Blastp_CBE
49.47
40%
-11
- C3 -
-
3A8W
1
KPCI_HUMAN
B:
[11-315]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
------
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
I-------------------EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
Blastp_CBE
49.46
45%
8
- C3 -
-
3HDM
1
SGK1_HUMAN
A:
[35-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
P
S
D
------
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
H
K
A
E
E
V
---
F
Y
A
V
K
V
L
Q
K
K
-
A
-
I
L
-----------------------
V
L
L
K
--
N
V
----
K
---
H
P
-
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
S
Q
G
H
I
V
L
T
D
F
G
-
L
------------------------------
C
K
E
N
I
-
E
H
N
-
S
T
-----
T
S
--
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
-
L
P
P
F
---
Y
---
S
R
----
N
T
A
E
----
M
Y
D
------
N
I
L
--
N
K
--
P
L
--
Q
L
---
K
--
P
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
--
R
L
G
A
K
--
D
-
D
F
M
E
-
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
407
Blastp_CBE
49.38
39%
-15
- C3 -
-
4IAK
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
386
Blastp_CBE
49.38
39%
-13
- C3 -
-
4WBB
1
KAPCA_MOUSE
B:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
438
Blastp_CBE
49.35
38%
-10
- C3 -
-
2VO3
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
250
Blastp_CBE
49.33
39%
-13
- C3 -
-
6E9L
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
327
Blastp_CBE
49.32
39%
-12
- C3 -
-
6EM2
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
255
Blastp_CBE
49.31
39%
-14
- C3 -
-
2VO7
2
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
261
Blastp_CBE
49.30
37%
15
- C3 -
-
4UJB
3
KAPCA_HUMAN
A:
[5-329]
-------------------------------------------------------------------------------------------------------------------------------
A
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
314
Blastp_CBE
49.27
39%
-10
- C3 -
-
6I2D
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
293
Blastp_CBE
49.27
39%
-14
- C3 -
-
3L9N
1
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
---
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
429
Blastp_CBE
49.29
39%
-18
- C3 -
-
3ZO3
9
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
323
Blastp_CBE
49.25
39%
-9
- C3 -
-
6EMD
1
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
219
Blastp_CBE
49.27
39%
-8
- C3 -
-
6MM8
6
KAPCA_MOUSE
C:
[27-339]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
222
Blastp_CBE
49.26
39%
-16
- C3 -
-
6MM6
1
KAPCA_MOUSE
E:
[27-339]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
185
Blastp_CBE
49.25
39%
-17
- C3 -
-
6F14
2
KAPCA_CRIGR
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
-----
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
198
Blastp_CBE
49.24
39%
-19
- C3 -
-
1BX6
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
410
Blastp_CBE
49.16
39%
-13
- C3 -
-
4IAD
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
329
Blastp_CBE
49.19
39%
-19
- C3 -
-
6EH2
2
KAPCA_CRIGR
A:
[41-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
----
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
196
Blastp_CBE
49.21
39%
-20
- C3 -
-
4NTT
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
138
Blastp_CBE
49.19
40%
-13
- C3 -
-
6ILZ
1
KPCI_HUMAN
C:
[11-343]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
I-------------------DYLFQ-
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
384
Blastp_CBE
49.11
39%
-16
- C3 -
-
5JR7
1
KAPCA_MOUSE
C:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
396
Blastp_CBE
49.16
39%
-20
- C3 -
-
3TNQ
1
KAPCA_MOUSE
B:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
299
Blastp_CBE
49.15
36%
17
- C3 -
-
2VO0
4
KAPCA_BOVIN
A:
[9-329]
-----------------------------------------------------------------------------------------------------------------------------------
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
297
Blastp_CBE
49.13
38%
-13
- C3 -
-
2GNJ
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
I
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
262
Blastp_CBE
49.11
37%
14
- C3 -
-
3VQH
2
KAPCA_HUMAN
A:
[5-329]
-------------------------------------------------------------------------------------------------------------------------------
A
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
372
Blastp_CBE
49.10
37%
10
- C3 -
-
4C36
1
KAPCA_BOVIN
A:
[14-329]
----------------------------------------------------------------------------------------------------------------------------------------
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
Y
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
415
Blastp_CBE
49.08
37%
12
- C3 -
-
3ZO2
4
KAPCA_BOVIN
A:
[8-329]
----------------------------------------------------------------------------------------------------------------------------------
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
216
Blastp_CBE
49.06
37%
6
- C3 -
-
1STC
1
KAPCA_BOVIN
E:
[15-328]
------------------------------------------------------------------------------------------------------------------------------------------
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
346
Blastp_CBE
49.02
39%
-10
- C3 -
-
5N3O
6
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
193
Blastp_CBE
48.99
39%
-13
- C3 -
-
1JBP
2
KAPCA_MOUSE
E:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
E
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
298
Blastp_CBE
48.91
37%
13
- C3 -
-
4WB6
1
KAPCA_HUMAN
B:
[8-328]
-----------------------------------------------------------------------------------------------------------------------------------
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
R
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
233
Blastp_CBE
48.88
39%
-10
- C3 -
-
1REJ
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
214
Blastp_CBE
48.88
37%
9
- C3 -
-
1SVG
1
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
194
Blastp_CBE
48.87
39%
-18
- C3 -
-
2GNF
1
KAPCA_BOVIN
A:
[42-328]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
------
F
E
R
I
K
T
I
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
191
Blastp_CBE
48.87
39%
-13
- C3 -
-
1CDK
2
KAPCA_PIG
A:
[42-328]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
F
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
296
Blastp_CBE
48.83
38%
-16
- C3 -
-
2GNL
1
KAPCA_BOVIN
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
I
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
226
Blastp_CBE
48.83
39%
-13
- C3 -
-
4DIN
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124
Blastp_CBE
48.80
38%
-17
- C3 -
-
5LIH
3
KPCI_HUMAN
B:
[7-341]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
-----------------
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
I-------------------EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
EPV
Q
----
L
P
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
258
Blastp_CBE
48.74
38%
-16
- C3 -
-
3O7L
2
KAPCA_MOUSE
B:
[38-332]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
----
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
I
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
I
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
213
Blastp_CBE
48.72
37%
9
- C3 -
-
1VEB
1
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
190
Blastp_CBE
48.62
39%
-14
- C3 -
-
1CDK
2
KAPCA_PIG
B:
[42-328]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
F
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
D
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
259
Blastp_CBE
48.61
37%
14
- C3 -
-
5BX7
4
KAPCA_HUMAN
A:
[6-329]
--------------------------------------------------------------------------------------------------------------------------------
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
374
Blastp_CBE
48.58
37%
9
- C3 -
-
4C34
3
KAPCA_BOVIN
A:
[11-329]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
Y
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
-
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
-
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
125
Blastp_CBE
48.55
38%
-7
- C3 -
-
5LIH
3
KPCI_HUMAN
A:
[7-341]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
K
K
T
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
---------------W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IV----------------
N
T
EDYLFQ
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
EPV
Q
----
L
P
D
---
D
D
D
--
I
--
V
---
R
--
K
--
I
D
Q
-----
S
E
--
F
E
G
F
E
Y
I
N
P
L
L
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
450
Blastp_CBE
48.53
39%
-12
- C3 -
-
4WB7
1
KAPCA_HUMAN
B:
[97-383]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
139
Blastp_CBE
48.50
40%
-16
- C3 -
-
6ILZ
1
KPCI_HUMAN
A:
[11-315]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IV------------------DYLFQ-
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
277
Blastp_CBE
48.49
39%
-15
- C3 -
-
3POO
2
KAPCA_HUMAN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
----
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
403
Blastp_CBE
48.44
39%
-13
- C3 -
-
4IB1
1
KAPCA_MOUSE
A:
[44-334]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
187
Blastp_CBE
48.39
37%
7
- C3 -
-
2GNH
2
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
I
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
199
Blastp_CBE
48.37
39%
-20
- C3 -
-
1BKX
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
316
Blastp_CBE
48.33
39%
-10
- C3 -
-
6I2B
2
KAPCA_CRIGR
A:
[41-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
H
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
428
Blastp_CBE
48.26
39%
-10
- C3 -
-
5VHB
1
KAPCA_BOVIN
A:
[39-329]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
-----
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136
Blastp_CBE
48.07
40%
-14
- C3 -
-
6ILZ
1
KPCI_HUMAN
G:
[11-317]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
IV------------------DYLFQ-
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
---
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
263
Blastp_CBE
48.04
37%
11
- C3 -
-
3AGL
1
KAPCA_HUMAN
B:
[15-329]
-----------------------------------------------------------------------------------------------------------------------------------------
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
241
Blastp_CBE
48.00
39%
-18
- C3 -
-
5VIB
1
KAPCA_BOVIN
A:
[39-349]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
----
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
192
Blastp_CBE
47.97
39%
-15
- C3 -
-
2QUR
1
KAPCA_MOUSE
A:
[38-324]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
P
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
254
Blastp_CBE
47.95
39%
-9
- C3 -
-
3AG9
1
KAPCA_BOVIN
B:
[39-351]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
186
Blastp_CBE
47.95
37%
5
- C3 -
-
2GNI
1
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
I
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
412
Blastp_CBE
47.85
37%
11
- C3 -
-
1XH7
1
KAPCA_BOVIN
A:
[10-328]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
N
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
H
M
---
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
264
Blastp_CBE
47.78
37%
14
- C3 -
-
3AGL
1
KAPCA_HUMAN
A:
[11-329]
-------------------------------------------------------------------------------------------------------------------------------------
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
436
Blastp_CBE
47.67
37%
13
- C3 -
-
4WB6
1
KAPCA_HUMAN
A:
[13-328]
----------------------------------------------------------------------------------------------------------------------------------------
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
R
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
311
Blastp_CBE
47.60
38%
-8
- C3 -
-
3FHI
1
KAPCA_MOUSE
A:
[38-328]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
L
D
Q
------
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
S
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
A
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
451
Blastp_CBE
47.56
39%
-11
- C3 -
-
4WB7
1
DNJB1_HUMAN (first)
A:
[97-383]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
------
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
290
Blastp_CBE
47.48
36%
16
- C3 -
-
3MVJ
1
KAPCA_HUMAN
A:
[36-349]
-------------------------------------------------------------------------------------------------------------------------------------------
V
K
E
F
L
A
--
K
A
K
E
D
F
L
K
K
W
E
-
S
P
A
Q
N
T
A
H
LDQ---
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
467
Blastp_CBE
47.42
37%
-44
- C3 -
-
2JAM
3
KCC1G_HUMAN
B:
[11-289]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
M
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
K
----
S
S
L
E
N
E
I
A
V
L
K
K
I
K
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
Y
L
T
P
E
E
N
S
K
I
M
-
I
T
D
F
G
L
S
K
M
--
E
Q
N
G
I
M
S
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
---
E
T
E
S
K
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
G
N
T
A
L
H
R
D
I
Y
P
S
V
S
L
-
Q
I
Q
K
N
F
A
K
------------------------------------
67
Blastp_CBE
47.37
45%
11
- C3 -
-
3HDN
1
SGK1_HUMAN
A:
[35-316]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
P
S
D
------
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
H
K
A
E
E
V
---
F
Y
A
V
K
V
L
Q
K
K
-
A
-
I
L
-----------------------
V
L
L
K
--
N
V
----
K
---
H
P
-
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
-
S
Q
G
H
I
V
L
T
D
F
G
-
L
------------------------------
C
K
E
N
I
-
E
H
N
-
S
T
-----
T
S
--
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
-
L
P
P
F
---
Y
---
S
R
----
N
T
A
E
----
M
Y
D
------
N
I
L
--
N
K
--
P
L
--
Q
L
---
K
--
P
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
--
R
L
G
A
K
--
D
-
D
F
M
E
-
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
131
Blastp_CBE
46.69
43%
-6
- C3 -
-
1XJD
1
A:
[19-335]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
---
F
K
K
T
N
Q
F
F
A
I
K
A
L
-
K
K
-
D
-
V
V
--
L
--
M
-
D
-
D
-
D
V
-
E
-
C
T
M
V
E
K
R
V
L
-
S
--
L
A
W---
E
---
H
P
-
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
-
K
D
G
H
I
K
I
A
D
F
G
-
M
------------------------------
C
K
E
N
M
-
L
G
D
-
A
K
-----
T
---
N
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
-
Q
S
P
F
---
H
---
G
Q
----
D
E
E
E
----
L
F
H
------
S
I
R
--
M
D
--
N
P
--
F
Y
---
P
--
R
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
--
R
L
G
V
R
G
-
D
------
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
P
------
S
P
F
D
C
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
288
Blastp_CBE
45.81
36%
20
- C3 -
-
3MVJ
1
KAPCA_HUMAN
E:
[36-349]
-------------------------------------------------------------------------------------------------------------------------------------------
V
K
E
F
L
A
--
K
A
K
E
D
F
L
K
K
W
E
-
S
P
A
Q
N
T
A
H
LDQ---
F
E
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
L
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137
Blastp_CBE
45.60
40%
-2
- C3 -
-
6ILZ
1
KPCI_HUMAN
E:
[12-317]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
D
--
R
I
Y
A
M
K
V
V
-
K
K
-
E
-
L
V
--
N
--
D
-
D
-
E
-
D
I
-
D
W
V
Q
T
-
E
K
H
V
F
-
E
--
Q
A
S---
N
---
H
P
-
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
-
S
E
G
H
I
K
L
T
D
Y
G
-
M
------------------------------
C
K
E
G
L
--
R
P
-
G
D
-----
T
T
--
S
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
-
R
S
P
F
---
D
I-------------------DYLFQ-
V
I
L
--
E
K
--
Q
I
--
R
I
---
P
--
R
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
--
R
L
G
C
H
P
-
Q
T
G
F
A
D
-
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
468
Blastp_CBE
42.86
37%
-44
- C3 -
-
2JAM
3
KCC1G_HUMAN
A:
[11-290]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
F
M
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
K
----
S
S
L
E
N
E
I
A
V
L
K
K
I
K
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
Y
L
T
P
E
E
N
S
K
I
M
-
I
T
D
F
G
L
S
K
M
--
E
Q
N
G
I
M
S
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
---
E
T
E
S
K
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
G
N
T
A
L
H
R
D
I
Y
P
S
V
S
L
-
Q
I
Q
K
N
F
A
K
S
-----------------------------------
380
Blastp_CBE
42.69
36%
28
- C3 -
-
3AMA
1
KAPCA_HUMAN
A:
[2-329]
-----------------------------------------------------------------------------------------------------------------------------
G
N
A
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
R
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
Q
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
-----
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
379
Blastp_CBE
39.20
36%
25
- C3 -
-
3AMB
1
KAPCA_HUMAN
A:
[4-329]
-------------------------------------------------------------------------------------------------------------------------------
A
A
A
A
K
K
G
E
Q
E
S
V
K
E
F
L
A
K
AK
E
D
F
L
K
K
W
E
S
P
A
-
Q
N
T
A
H
L
D
Q
------
F
E
R
I
R
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
---
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
-
K
-
V
V
--
K
--
L
-
K
-
Q
-
I
E
-
H
-
T
L
N
-
E
K
R
I
Q
-
Q
--
A
V
----
N
---
F
P
-
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
-
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
------------------------------
A
K
R
V
------
K
G
-----
R
T
--
W
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
---
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-
Y
P
P
F
---
F
---
A
D
----
Q
P
I
Q
----
I
Y
E
------
K
I
V
--
S
G
--
K
V
--
R
F
---
P
--
S
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
--
R
F
G
N
L
K
-
N
-
G
V
N
D
-
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
-----
F
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
Blastp_CBE
25.03
45%
23
- C3 -
-
4EJN
3
AKT1_HUMAN
A:
[22-438]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
P
K
H
RVTMNE
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
E
K
A
L
M
K
T
G
R
Y
Y
A
M
K
I
L
-
K
K
-
E
-
V
I
--
V
--
A
-
K
-
D
-
E
V
A
H
-
T
L
T
-
E
N
R
V
L
-
Q
--
N
S
----
R
---
H
P
-
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
-------------
D
L
K
L
E
N
L
M
L
D
-
K
D
G
H
I
K
I
T
D
F
G
-
L
------------------------------
C
K
E
G
I
-
K
D
G
-
A
T
-----
M
K
--
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
-
R
L
P
F
---
Y
---
N
Q
----
D
H
E
K
----
L
F
E
------
L
I
L
--
M
E
--
E
I
--
R
F
---
P
--
R
T
---
L
G
P
-----
L
S
G
L
L
K
K
D
P
K
Q
--
R
L
G
G
G
S
-
E
-
D
A
K
E
-
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
---
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
-
* C *
-
-
:
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------