@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CTRO_HUMAN: (2020-09-07 )
MLKFKYGARNPLDAGAAEPIASRASRLNLFFQGKPPFMTQQQMSPLSREGILDALFVLFEECSQPALMKIKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDEPEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSDQVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKGCHLFGAGKIENGLCICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV
Atome Classification :
(350 SA)
.........10........20........30..--......40..---------......50........60........70........80........90........100.......110......---.-120--........130.......140.......150.-..-.....160.......170.......180....---...190.......200.......210..-.....220.......230.......240........250......-.260.......270......-.280.......290.......300.-......310.---...----..------.320...-----.--.-..330...--....340-.-------..-..--..------350-----.-.--------.------.....360.--.....--.--.--.--370.--........380.......390.....-...400.....---...410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......1970......1980......1990......2000......2010......2020....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
L
K
F
KYGARNPLDAGAA
E
P
I
A
S
R
A
S
R
L
N
L
F
FQG--KPPF
M
T
Q
Q
QM---------SPLSRE
G
I
L
D
A
L
F
V
L
F
E
ECSQ
P
A
L
M
K
I
K
H
V
S
N
F
V
R
K
Y
S
D
T
I
A
E
L
Q
E
LQPSAKDF
E
V
R
S
LVGCG
H
F
A
E
V
Q
V
V
R
EKA---T-G
D
---
I
Y
A
M
K
V
M
K
K
K
A
L
L
A
Q
E
Q
V
S
F
F
E
E
E
R
N
I
L
S-RS-TS-PWI
P
Q
L
Q
Y
A
FQDKN
H
L
Y
L
V
M
E
YQPG
G
D
L
L
S
L
L
---
N
R
Y
E
D
Q
L
D
E
N
L
I
Q
F
Y
L
A
E
L
I
L
A
V
H
S
V
H
L
-
M
G
Y
V
HRDIKPE
N
I
L
VDRTG
H
I
K
L
V
DFG-SAAKMNSN
K
M
V
N
AKLPI-GTPDYMA
P
E
V
L
T
V
MNGDGKG-TYGLDC
D
W
W
S
V
G
V
I
A
Y
E
M
I
YGRSPF-AEGTSA
R
T
F
N
---
N
I
M
----
N
F
------
Q
R
F
LKFP-----D--D-PKV
S
S
D
F
L
--
D
L
I
Q
S
L
L-C-------G
Q
-
K
E
--R
L
------
K
F------E-G--------L------CC
H
P
F
F
--
S
--KIDWN--N--I--R--N--S--PPPFVPTLKSDDDTSNFDE-PEKNSW-VSSS-PCQLSP---SGFSGEEL
P
F
VGF
S
Y
S
K
A
L
GILGR
S
E
S
V
V
SGLDSPAK
T
S
S
M
E
K
K
L
L
I
K
S
K
ELQ
D
S
Q
D
K
C
H
K
M
E
Q
E
M
T
R
L
H
R
R
V
S
E
V
E
A
V
L
S
Q
K
E
V
E
L
K
A
S
E
T
Q
R
S
L
L
E
Q
D
L
A
T
Y
I
T
E
C
S
S
L
K
R
S
L
E
Q
A
R
M
EVSQE
D
D
K
A
L
Q
L
L
H
D
I
R
E
Q
S
R
K
L
Q
E
I
K
E
Q
E
Y
Q
A
Q
V
E
E
M
R
L
M
M
N
Q
L
E
E
D
L
V
S
A
R
R
RS
D
L
Y
E
S
E
L
R
E
S
R
L
A
A
E
E
F
K
R
K
A
T
E
C
Q
H
K
L
L
KAKDQGKPEV
G
E
Y
A
K
L
E
KI
N
A
E
Q
Q
L
K
I
Q
E
L
Q
E
K
L
E
K
A
V
KAST
E
A
T
E
L
L
Q
N
I
R
Q
A
K
E
R
A
E
R
E
L
E
K
L
QNRED
S
S
E
G
I
R
K
K
L
V
E
A
E
E
L
E
E
K
H
R
E
AQV
S
A
Q
H
L
E
V
H
L
K
Q
K
E
Q
H
Y
E
E
K
I
K
V
L
D
N
Q
I
K
K
D
LA
D
K
E
T
L
E
N
M
M
Q
R
H
E
E
E
A
H
E
KG
K
I
L
S
E
Q
K
A
M
I
N
A
M
D
S
K
I
R
S
L
E
Q
R
I
V
E
L
S
E
A
NKLAANSS
L
F
T
QRN
M
K
A
Q
E
E
M
I
S
E
L
R
QQ
K
F
Y
L
ETQAGKL
E
A
Q
N
R
K
L
E
E
Q
L
E
K
I
SHQDHSD
K
N
R
L
L
E
L
E
T
R
L
R
E
VS
L
E
H
E
E
Q
K
L
E
L
K
R
Q
L
T
E
L
Q
L
S
L
Q
E
R
E
S
Q
L
T
A
L
Q
A
A
R
A
A
L
E
S
Q
L
R
Q
A
K
T
E
L
E
E
T
T
A
E
A
E
E
E
I
Q
A
L
T
A
H
R
D
E
I
Q
R
K
F
D
A
L
RNS
C
T
V
I
T
D
L
E
E
Q
L
N
Q
L
T
EDNAELNNQ
N
F
Y
L
S
KQLDEASGAN
D
E
I
V
Q
L
R
S
E
V
D
H
L
R
R
E
I
T
E
R
E
M
Q
L
T
S
Q
K
Q
T
M
E
A
L
K
T
T
C
T
M
L
E
E
Q
V
M
D
L
E
AL
N
D
E
L
L
E
K
E
R
Q
W
E
A
W
R
S
V
LGDE
K
S
Q
F
E
C
R
V
R
E
L
Q
R
M
L
D
T
E
K
Q
S
R
A
R
A
D
Q
R
I
T
E
S
R
Q
V
V
E
L
A
V
K
E
H
K
A
E
I
L
A
L
Q
Q
A
L
K
E
QKL
K
A
E
S
L
S
D
K
L
N
D
L
E
K
K
H
A
M
L
E
M
N
A
R
S
L
Q
Q
K
L
E
T
E
R
E
L
K
Q
R
L
L
E
E
Q
A
K
L
Q
Q
Q
M
D
L
Q
K
N
H
I
F
R
L
T
Q
G
L
Q
E
A
L
D
R
A
D
L
L
K
TERS
D
L
E
Y
Q
LE
N
I
Q
V
L
Y
SH
E
K
V
K
MEGTI
S
Q
Q
T
K
L
I
D
F
L
Q
A
KMDQ
P
A
K
K
K
K
G
L
F
S
RRKEDPALPTQVPL
Q
Y
N
E
L
K
L
A
L
E
K
E
K
A
R
C
A
E
L
E
E
A
L
Q
K
T
R
I
E
L
R
S
A
R
E
E
A
AHRKATDHPHPST
P
A
T
A
R
Q
Q
I
A
M
S
A
I
VRSPEHQPSA
M
S
L
LAPPSSRRKESS
T
P
E
E
F
S
R
R
L
K
E
R
M
HHNIP
H
R
F
NVGLNMR
A
T
K
C
A
V
C
L
D
T
V
H
F
G
R
Q
A
S
K
C
L
E
C
Q
V
M
CHPKCSTCLPATCGL
P
A
E
Y
A
T
H
F
T
E
A
F
C
R
DKMNSPGLQTKEPSSSLH
L
E
G
W
MKVPRNNKRGQQGW
D
R
K
Y
I
V
L
EG
S
K
V
L
I
YDN
E
A
R
EAGQR
P
V
E
E
F
E
L
CLPDG
D
V
S
I
H
GAV
G
A
S
E
L
ANTAKADV
P
Y
I
L
K
MESHPHTTCWPG
R
T
L
Y
L
LAPSFP
D
K
Q
R
W
V
T
A
L
E
S
V
V
AGGRVS
R
E
K
A
E
A
D
A
K
L
L
GN
S
L
L
KLEGDDRLDMNCTLPFSD
Q
V
V
L
V
GTEE
G
L
Y
A
L
N
V
L
K
N
S
LTHVPGI
G
A
V
F
Q
I
Y
I
I
K
D
L
E
K
L
L
M
IAGEE
R
A
L
C
L
V
D
V
K
K
V
K
Q
S
L
A
Q
SHLPAQPDIS
P
N
I
F
E
A
V
KG
C
H
L
FGAGKIEN
G
L
C
I
C
AAMP
S
K
V
V
I
L
R
YNE
N
L
S
K
Y
C
I
R
K
EIETSEP
C
S
C
I
H
FT
N
Y
S
I
L
IGTN
K
F
Y
E
I
D
M
K
Q
Y
T
L
E
E
F
LDKNDHSLA
P
A
V
F
AASSNSF
P
V
S
I
V
Q
VNSAGQRE
E
Y
L
L
C
F
H
E
F
G
V
F
V
D
SYGRRSRTDDLKWSRL
P
L
A
F
A
YRE
P
Y
L
F
V
T
HFNS
L
E
V
I
E
I
Q
ARSSAGTP
A
R
A
Y
LDIPNPRYLGPAISS
G
A
I
Y
L
ASSYQD
K
L
R
V
I
C
CKGNLVKESGTEHHRGPSTSRSSPNKRGPP
T
Y
N
E
H
I
T
K
R
V
ASSPAPPEGPSHPREPST
P
H
R
Y
R
E
G
R
T
E
L
RRDKSPGRPLEREKSPG
R
M
L
S
T
R
RERSPGRLFEDSSRGRLPA
G
A
VR
T
P
L
S
Q
V
N
K
V
WDQSSV
70
Blastp_CBE
94.17
44%
-98
- C4 -
-
5HVU
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
542
Fugue
94.04
43%
-86
- C4 -
-
4AW2
5
MRCKA_RAT
A:
[1-416]
---------------------
S
G
E
V
R
L
R
Q
L
E
Q
F
--
I
L
D
G
P
A
Q
T
N
G
---------
Q
C
F
S
V
E
T
L
L
D
I
L
I
C
L
Y
D
E
C
N
N
S
P
L
R
R
E
K
N
I
L
E
Y
L
E
W
A
K
P
F
T
S
K
V
K
Q
M
R
L
H
R
E
D
F
E
I
L
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
L
K
N
---
A
-
D
K
---
V
F
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
S
-
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
M
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
L
M
E
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
G
-
G
K
G
-
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
K
E
R
F
Q
F
P
-----
T
--
Q
V
T
D
V
S
E
N
A
K
--
D
L
I
R
R
L
I
-
C
-------
S
R
-
E
H
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
P
F
F
--
S
--
G
I
D
W
D
--
N
--
I
--
R
--
N
--
C
--
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
-
D
-----------------------
S
G
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
R
S
C
L
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
Blastp_CBE
93.97
44%
-96
- C4 -
-
5WNE
1
ROCK1_HUMAN
D:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
Blastp_CBE
93.88
44%
-101
- C4 -
-
5KKT
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
----
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
Blastp_CBE
93.87
44%
-96
- C4 -
-
5WNF
3
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
Blastp_CBE
93.80
44%
-95
- C4 -
-
4YVC
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.79
44%
-99
- C4 -
-
4UAK
2
MRCKB_HUMAN
A:
[25-406]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
--------------------SH-
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
Blastp_CBE
93.74
44%
-101
- C4 -
-
5KKS
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
---
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
Blastp_CBE
93.73
44%
-95
- C4 -
-
2ETK
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83
Blastp_CBE
93.56
44%
-95
- C4 -
-
2ESM
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
Blastp_CBE
93.55
44%
-93
- C4 -
-
5WNF
1
ROCK1_HUMAN
D:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Blastp_CBE
93.46
44%
-89
- C4 -
-
3TV7
2
ROCK1_HUMAN
A:
[18-394]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
93.46
44%
-99
- C4 -
-
5OTE
2
MRCKB_HUMAN
A:
[25-406]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
--
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
----------------
I
L
P
P
GSH
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
Blastp_CBE
93.36
44%
-92
- C4 -
-
3D9V
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Blastp_CBE
93.31
44%
-97
- C4 -
-
5WNG
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
Blastp_CBE
93.30
44%
-96
- C4 -
-
5WNE
2
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
----
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
Blastp_CBE
93.27
44%
-92
- C4 -
-
2ETR
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Blastp_CBE
93.25
44%
-92
- C4 -
-
3V8S
1
ROCK1_HUMAN
C:
[18-394]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Blastp_CBE
93.23
44%
-95
- C4 -
-
5WNG
1
ROCK1_HUMAN
D:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
93.22
44%
-92
- C4 -
-
5OTF
3
MRCKB_HUMAN
A:
[25-406]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
--------------
E
I
L
P
P
GSH
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
Blastp_CBE
93.11
44%
-98
- C4 -
-
5KKT
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
----
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
--------
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
Blastp_CBE
93.03
44%
-97
- C4 -
-
4YVE
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
------
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
Blastp_CBE
92.93
44%
-94
- C4 -
-
5BML
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
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V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
----
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
92.93
43%
-97
- C4 -
-
3D9V
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93
Blastp_CBE
92.80
43%
-99
- C4 -
-
4L6Q
1
ROCK2_HUMAN
A:
[24-402]
------------------------------------------------------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
R
Q
H
P
F
F
KN
D
--
Q
W
H
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
E
D
---D
V
E
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
92.64
44%
-95
- C4 -
-
4UAL
2
MRCKB_HUMAN
A:
[25-406]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
---
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
--
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
---------------
I
L
P
P
H--
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
Blastp_CBE
92.62
44%
-93
- C4 -
-
5HVU
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
-----
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
Blastp_CBE
92.55
44%
-103
- C4 -
-
5UZJ
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
----
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
------
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
------
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Blastp_CBE
92.53
45%
-91
- C4 -
-
3QFV
3
MRCKB_HUMAN
B:
[23-404]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
------------------------
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
Blastp_CBE
92.52
44%
-97
- C4 -
-
5KKS
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
------
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92
Blastp_CBE
92.28
43%
-94
- C4 -
-
4L6Q
1
ROCK2_HUMAN
B:
[24-402]
------------------------------------------------------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
R
Q
H
P
F
F
KN
D
--
Q
W
H
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
E
D
---D
V
E
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
92.21
43%
-99
- C4 -
-
4YVC
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
-----
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
--------
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
92.17
43%
-97
- C4 -
-
2ETK
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Blastp_CBE
92.13
44%
-98
- C4 -
-
2V55
1
ROCK1_HUMAN
C:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
---
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
92.05
43%
-94
- C4 -
-
2ESM
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
558
HHSearch
92.02
41%
-86
- C4 -
-
4AW2
5
MRCKA_RAT
A:
[5-416]
----------------------
R
L
R
Q
L
E
Q
F
I
L
D
--
G
P
A
Q
T
---
N
G
---------
Q
C
F
S
V
E
T
L
L
D
I
L
I
C
L
Y
D
E
C
N
N
S
P
L
R
R
E
K
N
I
L
E
Y
L
E
W
A
K
P
F
T
S
K
V
K
Q
M
R
L
H
R
E
D
F
E
I
L
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
L
K
N
---
A
-
D
K
---
V
F
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
S
-
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
M
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
L
M
E
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
G
G
K
G
-
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
K
E
R
F
Q
F
P
-----
T
--
Q
V
T
D
V
S
E
N
A
K
--
D
L
I
R
R
L
I
-
C
S------
R
E
-
H
R
LG
Q
N
------
G
I
------
E
-
D
--------
F
------
K
K
H
P
F
F
--
S
--
G
I
D
W
D
--
N
--
I
--
R
--
N
--
C
--
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
-
D
-----------------------
S
G
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
R
S
C
L
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
Blastp_CBE
91.92
44%
-103
- C4 -
-
5UZJ
1
ROCK1_HUMAN
B:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
---------
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
91.85
43%
-95
- C4 -
-
5BML
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
-----
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
------
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
560
HHSearch
91.74
44%
-88
- C4 -
-
5OTF
3
MRCKB_HUMAN
A:
[32-416]
-------------------------------------------------------------
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
H-
V
-
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
S------
R
E
-
R
R
LG
Q
N
------
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
----------
E
I
-
L
P
P
G
S
H
---
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
91.79
43%
-90
- C4 -
-
4AW2
4
MRCKA_RAT
A:
[25-413]
--------------------------------------------------------
F
S
V
E
T
L
L
D
I
L
I
C
L
Y
D
E
C
N
N
S
P
L
R
R
E
K
N
I
L
E
Y
L
E
W
A
K
P
F
T
S
K
V
K
Q
M
R
L
H
R
E
D
F
E
I
L
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
L
K
N
---
A
-
D
K
---
V
F
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
S
-
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
M
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
L
M
E
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
G
-
G
K
G
-
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
K
E
R
F
Q
F
P
-----
T
--
Q
V
T
D
V
S
E
N
A
K
--
D
L
I
R
R
L
I
-
C
-------
S
R
-
E
H
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
P
F
F
--
S
--
G
I
D
W
D
--
N
--
I
--
R
--
N
--
C
--
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
-
D
-----------------------
S
G
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
R
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
91.79
44%
-91
- C4 -
-
3QFV
2
MRCKB_HUMAN
A:
[23-404]
------------------------------------------------------
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
-------------------------
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
91.74
42%
-102
- C4 -
-
6E9W
1
ROCK1_HUMAN
A:
[37-427]
---------------------------
T
R
F
--
E
--
K
M
D
N
L
L
R
D
P
K
---------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
--------
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
---------
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
91.73
43%
-98
- C4 -
-
2V55
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
562
HHSearch
91.72
44%
-92
- C4 -
-
5OTE
2
MRCKB_HUMAN
A:
[30-416]
-----------------------------------------------------------
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
--
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
H-
V
-
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
S------
R
E
-
R
R
LG
Q
N
------
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
------------
I
-
L
P
P
G
S
H
---
T
G
F
S
G
L
H
L
P
F
I
G
F
T
F
T
T
E
S
C
F
S
D
R
G
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
91.71
43%
-94
- C4 -
-
2ETR
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
E
E
D
K
G
-
E
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
91.64
43%
-99
- C4 -
-
4YVE
1
ROCK1_HUMAN
A:
[23-399]
------------------------------------------------------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
------
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
Blastp_CBE
91.40
42%
-102
- C4 -
-
2F2U
1
ROCK2_BOVIN
A:
[24-402]
------------------------------------------------------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
Q
H
P
F
F
KN
D
--
Q
W
N
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
E
-----
V
E
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Blastp_CBE
90.91
42%
-96
- C4 -
-
6E9W
1
ROCK1_HUMAN
B:
[35-427]
-------------------------
F
E
T
R
F
--
E
--
K
M
D
N
L
L
R
D
P
K
---------
S
E
V
N
S
D
C
L
L
D
G
L
D
A
L
V
Y
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
------
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
-----
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
R
H
L
F
F
--
K
ND
Q
W
A
W
E
--
T
--
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
F
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95
Blastp_CBE
90.46
42%
-98
- C4 -
-
2F2U
1
ROCK2_BOVIN
B:
[24-402]
------------------------------------------------------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
Q
H
P
F
F
KN
D
--
Q
W
N
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
--------
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
564
HHSearch
89.15
43%
-99
- C4 -
-
6ED6
1
ROCK2_HUMAN
A:
[38-413]
-------------------------------------------------------
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
--
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
-------
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
D------
R
E
-
V
R
LG
R
N
------
G
V
------
E
-
E
--------
I
------
R
Q
H
P
F
F
--
K
--
N
D
Q
W
H
--
W
--
D
NI
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
--------
E
---
T
F
P
I
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94
Blastp_CBE
88.94
42%
-93
- C4 -
-
2H9V
1
ROCK2_BOVIN
A:
[24-402]
------------------------------------------------------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
G
D
--
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
K
Q
H
P
F
F
KN
D
--
Q
W
N
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
E
-----------
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
566
HHSearch
85.97
45%
-86
- C4 -
-
4YVC
1
ROCK1_HUMAN
B:
[65-402]
------------------------------------------------------------------------------------------------
K
I
R
D
L
R
M
K
A
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
S
---
T
-
R
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
--
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
N
K
E
G
M
V
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
G
--
G
D
G
-
Y
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
N
H
------
K
N
S
L
T
F
P
-----
D
--
D
-
N
D
I
S
K
E
A
K
--
N
L
I
C
A
F
L
-
T
D------
R
E
-
V
R
LG
R
N
------
G
V
------
E
-
E
--------
I
------
K
R
H
L
F
F
--
K
--
N
D
Q
W
A
--
W
ET
L
--
R
--
D
--
T
--
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
D
D
-
L
-------
E
E
T
-
F
--
P
I
P
---
K
A
F
V
G
N
Q
L
P
F
V
G
F
T
Y
Y
S
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
84.47
44%
8
- C4 -
-
3TKU
3
MRCKB_HUMAN
B:
[18-420]
---------------------------------SA
K
V
R
L
K
K
L
E
Q
L
LLDGPWRNE
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
-------------------------
F
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.18
43%
13
- C4 -
-
3TKU
3
MRCKB_HUMAN
A:
[18-420]
---------------------------------SA
K
V
R
L
K
K
L
E
Q
L
LLDGPWRNE
S
A
L
S
V
E
T
L
L
D
V
L
V
C
L
Y
T
E
C
S
H
S
A
L
R
R
D
K
Y
V
A
E
F
L
E
W
A
K
P
F
T
Q
L
V
K
E
M
Q
L
H
R
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
M
K
N
---
T
-
E
R
---
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
-
N
G
-
D
C
-
Q
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
---
S
K
F
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
-
S
C
L
K
M
N
D
D
G
T
V
Q
S
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
-
D
G
M
G
-
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-
Y
A
E
S
L
V
E
T
Y
G
---
K
I
M
----
N
H
------
E
E
R
F
Q
F
P
-----
S
--
H
V
T
D
V
S
E
E
A
K
--
D
L
I
Q
R
L
I
-
C
-------
S
R
-
E
R
--
R
L
GQN---
G
I
------
E
-
D
--------
F
------
K
K
H
A
F
F
--
E
--
G
L
N
W
E
--
N
--
I
--
R
--
N
--
L
--
E
A
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
D
V
-------------------------
S
G
L
H
L
P
F
I
G
F
T
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Blastp_CBE
81.94
43%
-29
- C4 -
-
6ED6
1
ROCK2_HUMAN
B:
[26-414]
---------------------------------R-
K
L
E
A
L
I
R
D
P
R
---------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
-------------
G
T
P
D
Y
I
S
P
E
V
L
K
S
---------
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
R
Q
H
P
F
F
KN
D
--
Q
W
H
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
-------
E
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
79.09
42%
20
- C4 -
-
6ED6
1
ROCK2_HUMAN
A:
[25-413]
---------------------------------QR
K
L
E
A
L
I
R
D
P
R
---------
S
P
I
N
V
E
S
L
L
D
G
L
N
S
L
V
L
D
L
D
F
P
A
L
R
K
N
K
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
H
K
A
---
S
-
Q
K
---
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
-
F
A
-
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
N
L
M
---
S
N
Y
D
--
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
S
-
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
-
T
C
M
K
M
D
E
T
G
M
V
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
S
Q
-------
F
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
-
Y
A
D
S
L
V
G
T
Y
S
---
K
I
M
----
D
H
------
K
N
S
L
C
F
P
-----
E
--
D
-
A
E
I
S
K
H
A
K
--
N
L
I
C
A
F
L
-
T
-------
D
R
-
E
V
--
R
L
------
G
R
------
N
-
G
VEE-----
I
------
R
Q
H
P
F
F
KN
D
--
Q
W
H
W
D
--
N
--
I
--
R
--
E
--
T
--
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
-
I
-------
E
T
F
-
P
I
---
P
---
K
A
F
V
G
N
Q
L
P
F
I
G
F
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
572
HHSearch
76.59
37%
-92
- C4 -
-
2JDO
2
AKT2_HUMAN
A:
[8-341]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
E
-
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
G
A
-
T
M
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
D
------
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
--------
E
I
R
F
P
----------
R
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
K------
D
P
-
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
--
V
--
Q
KK
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
--------------------
M
F
E
D
F
D
Y
I
A
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
271
Blastp_CBE
74.15
34%
-94
- C4 -
-
2UZT
1
KAPCA_BOVIN
A:
[29-317]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
234
Blastp_CBE
73.91
34%
-95
- C4 -
-
2OH0
1
KAPCA_BOVIN
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
237
Blastp_CBE
73.84
34%
-90
- C4 -
-
2F7E
1
KAPCA_BOVIN
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
235
Blastp_CBE
73.63
34%
-97
- C4 -
-
2F7Z
1
KAPCA_BOVIN
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
233
Blastp_CBE
73.60
34%
-90
- C4 -
-
2OJF
1
KAPCA_BOVIN
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
268
Blastp_CBE
73.27
34%
-92
- C4 -
-
2UZW
1
KAPCA_BOVIN
E:
[29-317]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
236
Blastp_CBE
73.26
34%
-88
- C4 -
-
2F7X
1
KAPCA_BOVIN
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
270
Blastp_CBE
73.25
34%
-93
- C4 -
-
2UZU
1
KAPCA_BOVIN
E:
[29-317]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
269
Blastp_CBE
72.86
34%
-87
- C4 -
-
2UZV
1
KAPCA_BOVIN
A:
[29-317]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
T
L
C
-----
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
575
HHSearch
70.87
35%
-57
- C4 -
-
3TXO
1
KPCL_HUMAN
A:
[23-349]
---------------------------------------------------------------------------------------------------------
D
N
F
E
F
I
R
V
L
G
K
G
S
F
G
K
V
M
L
A
R
V
K
E
---
T
-
G
D
---
L
Y
A
V
K
V
L
K
K
D
V
I
L
Q
D
D
D
V
E
C
T
M
T
E
K
R
I
L
S
-
L
A
R
N
H
-
P
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
---
Q
K
S
-
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
H
E
G
H
C
K
L
A
D
F
G
-
M
C
K
E
G
I
----------
C
-
G
T
P
D
Y
I
A
P
E
I
L
Q
E
------
M
-
L
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
H
A
P
F
-
E
A
E
N
E
D
D
L
F
E
---
A
I
L
----
N
D
------
E
--
V
V
Y
P
----------
T
W
L
H
E
D
A
T
--
G
I
L
K
S
F
M
-
T
K------
N
P
-
T
M
--
R
L
------
G
S
LTQGGE
H
-
A
--------
I
------
L
R
H
P
F
F
--
K
--
E
I
D
W
A
--
Q
--
L
--
N
HR
Q
--
I
--
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
D
P
-
D
F
I
K
E
E
-
P
V
L
T
-
P
I
D
E
G
H
----
L
P
M
I
N
Q
D
E
F
R
N
F
E
Y
V
S
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
569
HHSearch
70.78
33%
-37
- C4 -
-
4RA5
3
KPCT_HUMAN
A:
[4-331]
--------------------------------------------------------------------------------------------------------
I
E
D
F
E
L
H
K
M
L
G
K
G
S
F
G
K
V
F
L
A
E
F
K
K
---
T
-
N
Q
---
F
F
A
I
K
A
L
K
K
D
V
V
L
M
D
D
D
V
E
C
T
M
V
E
K
R
V
L
S
L
A
W
-
E
H
-
P
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
---
Q
S
C
-
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
K
D
G
H
I
K
I
A
D
F
G
-
M
C
K
E
N
M
L
G
D
-
A
K
T
N
E
F
C
-
G
T
P
D
Y
I
A
P
E
I
L
L
G
------
Q
-
K
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
Q
S
P
F
-
H
G
Q
D
E
E
E
L
F
H
---
S
I
R
----
M
D
------
N
--
P
F
Y
P
----------
R
W
L
E
K
E
A
K
--
D
L
L
V
K
L
F
-
V
R------
E
P
-
E
K
--
R
L
------
G
V
------
R
G
D
--------
I
------
R
Q
H
P
L
F
--
R
--
E
I
N
W
E
--
E
--
L
--
E
RK
E
--
I
--
D
P
P
F
R
P
K
V
K
S
P
F
D
C
S
N
F
D
K
-
E
F
L
N
E
K
-
P
R
L
S
-
F
A
D
R
A
L
----
I
N
S
M
D
Q
N
M
F
R
N
F
S
F
M
N
P
G
M
E
R
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113
Blastp_CBE
68.86
37%
-72
- C4 -
-
3TXO
1
A:
[24-315]
----------------------------------------------------------------------------------------------------------
N
F
E
F
I
R
V
L
G
K
G
S
F
G
K
V
M
L
A
R
V
K
E
---
T
-
G
D
---
L
Y
A
V
K
V
L
K
K
D
V
I
L
Q
D
D
D
V
E
C
T
M
T
E
K
R
I
L
S
-
L
A
R
N
H
-
P
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
---
Q
K
S
R
-
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
H
E
G
H
C
K
L
A
D
F
G
-
M
C
K
E
G
I
----------
C
-
G
T
P
D
Y
I
A
P
E
I
L
Q
E
M
-------
L
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
H
A
P
F
-
E
A
E
N
E
D
D
L
F
E
---
A
I
L
----
N
D
------
E
--
V
V
Y
P
TWLHE
D
--
A
-
T
G
I
L
K
S
F
M
--
T
K
N
P
T
M
R
-
L
-------
G
S
-
L
T
--
Q
G
------
G
E
------
H
-
A
--------
I
------
L
R
H
P
F
F
--
K
--
E
I
D
W
A
QL
N
--
H
--
R
--
Q
--
I
--
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
570
HHSearch
68.64
37%
-34
- C4 -
-
4GV1
5
AKT1_HUMAN
A:
[7-311]
--------------------------------------------------------------------------------------------------------
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
E
-
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
K
D
G
A
-
T
M
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
D
------
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
----------
R
T
L
G
P
E
A
K
--
S
L
L
S
G
L
L
-
K
K------
D
P
-
K
Q
--
R
L
GGGSE-
D
A
------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
--
Y
EK
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
361
Blastp_CBE
68.64
34%
-74
- C4 -
-
3IDC
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
181
Blastp_CBE
68.25
34%
-71
- C4 -
-
4Z84
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
165
Blastp_CBE
68.22
34%
-75
- C4 -
-
5M75
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
132
Blastp_CBE
68.14
35%
-71
- C4 -
-
3OXT
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
368
Blastp_CBE
68.03
34%
-72
- C4 -
-
1FMO
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
121
Blastp_CBE
68.02
35%
-70
- C4 -
-
5UZK
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134
Blastp_CBE
68.00
35%
-69
- C4 -
-
3OVV
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
162
Blastp_CBE
67.97
34%
-71
- C4 -
-
5N1E
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
201
Blastp_CBE
67.93
34%
-68
- C4 -
-
4YXS
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
190
Blastp_CBE
67.92
34%
-73
- C4 -
-
2C1A
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
342
Blastp_CBE
67.84
34%
-76
- C4 -
-
3QAL
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
A
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
Blastp_CBE
67.84
35%
-68
- C4 -
-
2GNI
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
I
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
189
Blastp_CBE
67.82
34%
-70
- C4 -
-
2C1B
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
188
Blastp_CBE
67.80
34%
-71
- C4 -
-
2VO7
2
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
176
Blastp_CBE
67.80
34%
-71
- C4 -
-
5LCQ
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
195
Blastp_CBE
67.79
34%
-71
- C4 -
-
4IJ9
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
340
Blastp_CBE
67.75
34%
-72
- C4 -
-
1YDS
1
KAPCA_BOVIN
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
186
Blastp_CBE
67.76
34%
-70
- C4 -
-
3ZO4
4
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
163
Blastp_CBE
67.74
34%
-71
- C4 -
-
5N1D
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
140
Blastp_CBE
67.74
35%
-72
- C4 -
-
1CDK
2
KAPCA_PIG
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
F
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
144
Blastp_CBE
67.68
35%
-68
- C4 -
-
2GNJ
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
I
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
371
Blastp_CBE
67.67
34%
-79
- C4 -
-
4NTT
1
KAPCA_MOUSE
B:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
532
Blastp_CBE
67.55
32%
-93
- C4 -
-
2PE1
5
PDPK1_HUMAN
A:
[8-283]
----------------------------------------------------------------------------------------------------------
D
F
K
F
G
K
I
L
G
E
G
S
F
S
T
V
V
L
A
R
E
L
A
---
T
-
S
R
---
E
Y
A
I
K
I
L
E
K
R
H
I
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
M
S
-
R
L
-
D
H
-
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
L
K
Y
I
---
R
K
I
-
G
S
F
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
L
E
Y
L
H
G
-
K
G
I
I
H
R
D
L
K
P
E
N
I
L
L
N
E
D
M
H
I
Q
I
T
D
F
G
-
T
A
K
V
L
S
--------
F
-
V
-
G
T
A
Q
Y
V
S
P
E
L
L
T
E
K
S
A
C
K
-------
S
S
D
L
W
A
L
G
C
I
I
Y
Q
L
V
A
G
L
P
P
F
-
R
A
G
N
E
Y
L
I
F
Q
---
K
I
I
----
K
L
------
E
--
Y
D
F
P
-----
E
-----
K
F
F
P
K
A
R
--
D
L
V
E
K
L
L
-
V
LDATKRL
G
C
-
E
E
--
M
E
------
G
Y
------
G
-
P
--------
L
------
K
A
H
P
F
F
--
E
--
S
V
T
W
E
--
N
--
L
--
H
--
Q
--
Q
--
T
P
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114
Blastp_CBE
67.61
35%
-71
- C4 -
-
3NX8
3
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
-
Q
-------
V
D
-
L
T
--
K
-------
R
F
------
G
-
N
--------
L
KNGVND
I
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
Blastp_CBE
67.59
35%
-69
- C4 -
-
2GNH
2
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
I
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
341
Blastp_CBE
67.52
34%
-69
- C4 -
-
1YDR
1
KAPCA_BOVIN
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
206
Blastp_CBE
67.55
34%
-71
- C4 -
-
1Q24
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
531
Blastp_CBE
67.53
32%
-92
- C4 -
-
2PE2
9
PDPK1_HUMAN
A:
[8-283]
----------------------------------------------------------------------------------------------------------
D
F
K
F
G
K
I
L
G
E
G
S
F
S
T
V
V
L
A
R
E
L
A
---
T
-
S
R
---
E
Y
A
I
K
I
L
E
K
R
H
I
I
K
E
N
K
V
P
Y
V
T
R
E
R
D
V
M
S
-
R
L
-
D
H
-
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
L
K
Y
I
---
R
K
I
-
G
S
F
D
E
T
C
T
R
F
Y
T
A
E
I
V
S
A
L
E
Y
L
H
G
-
K
G
I
I
H
R
D
L
K
P
E
N
I
L
L
N
E
D
M
H
I
Q
I
T
D
F
G
-
T
A
K
V
L
S
--------
F
-
V
-
G
T
A
Q
Y
V
S
P
E
L
L
T
E
K
S
A
C
K
-------
S
S
D
L
W
A
L
G
C
I
I
Y
Q
L
V
A
G
L
P
P
F
-
R
A
G
N
E
Y
L
I
F
Q
---
K
I
I
----
K
L
------
E
--
Y
D
F
P
-----
E
-----
K
F
F
P
K
A
R
--
D
L
V
E
K
L
L
-
V
LDATKRL
G
C
-
E
E
--
M
E
------
G
Y
------
G
-
P
--------
L
------
K
A
H
P
F
F
--
E
--
S
V
T
W
E
--
N
--
L
--
H
--
Q
--
Q
--
T
P
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
141
Blastp_CBE
67.52
35%
-70
- C4 -
-
6C0U
4
KAPCA_HUMAN
A:
[47-335]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
199
Blastp_CBE
67.50
34%
-70
- C4 -
-
1XH5
3
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
143
Blastp_CBE
67.50
35%
-72
- C4 -
-
2GNL
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
I
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129
Blastp_CBE
67.50
35%
-72
- C4 -
-
4UJ1
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
116
Blastp_CBE
67.50
35%
-70
- C4 -
-
5BX6
4
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
185
Blastp_CBE
67.48
34%
-66
- C4 -
-
4IE9
2
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
171
Blastp_CBE
67.48
34%
-71
- C4 -
-
5M0C
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
204
Blastp_CBE
67.47
34%
-69
- C4 -
-
3DND
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
135
Blastp_CBE
67.46
35%
-72
- C4 -
-
3OOG
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
363
Blastp_CBE
67.39
34%
-69
- C4 -
-
3FJQ
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
357
Blastp_CBE
67.39
34%
-73
- C4 -
-
4HPT
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
118
Blastp_CBE
67.42
35%
-71
- C4 -
-
3VQH
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
372
Blastp_CBE
67.37
34%
-79
- C4 -
-
4NTT
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
362
Blastp_CBE
67.40
34%
-69
- C4 -
-
3IDB
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
160
Blastp_CBE
67.39
34%
-73
- C4 -
-
5N32
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
-
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115
Blastp_CBE
67.39
35%
-73
- C4 -
-
5BX7
4
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
179
Blastp_CBE
67.37
34%
-70
- C4 -
-
4Z83
2
KAPCA_BOVIN
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
Blastp_CBE
67.36
35%
-67
- C4 -
-
2GNF
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
I
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
M
P
G
G
D
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
131
Blastp_CBE
67.33
35%
-68
- C4 -
-
3P0M
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
172
Blastp_CBE
67.32
34%
-70
- C4 -
-
5M0B
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
126
Blastp_CBE
67.33
35%
-71
- C4 -
-
4UJA
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
139
Blastp_CBE
67.32
35%
-71
- C4 -
-
1CDK
2
KAPCA_PIG
B:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
F
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
133
Blastp_CBE
67.31
35%
-67
- C4 -
-
3OWP
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
203
Blastp_CBE
67.29
34%
-68
- C4 -
-
3DNE
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
168
Blastp_CBE
67.29
34%
-71
- C4 -
-
5M6V
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
145
Blastp_CBE
67.28
35%
-72
- C4 -
-
3MVJ
1
KAPCA_HUMAN
E:
[64-352]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111
Blastp_CBE
67.28
35%
-102
- C4 -
-
5LOH
3
GWL_HUMAN
B:
[33-316]
------------------------------------------------------------------------------------------------------
P
S
I
E
E
F
S
I
V
K
P
I
S
R
G
A
F
G
K
V
Y
L
G
Q
K
G
------
G
K
---
L
Y
A
V
K
V
V
K
K
A
D
M
I
N
K
-------------
A
-
L
S
-
K
S
-
P
F
I
V
H
L
Y
Y
S
L
Q
S
A
N
N
V
Y
L
V
M
E
Y
L
I
G
G
D
V
K
S
L
L
---
H
I
Y
-
G
Y
F
D
E
E
M
A
V
K
Y
I
S
E
V
A
L
A
L
D
Y
L
H
R
-
H
G
I
I
H
R
D
L
K
P
D
N
M
L
I
S
N
E
G
H
I
K
L
T
D
F
G
--
L
----------------
G
T
P
D
Y
L
A
P
E
L
L
L
-----
G
R
--
A
H
G
P
A
V
D
W
W
A
L
G
V
C
L
F
E
F
L
T
G
I
P
P
F
-
N
D
E
T
P
Q
Q
V
F
Q
---
N
I
L
------------
K
R
D
I
P
W
P
-----
E
G-
E
-
E
K
L
S
D
N
A
Q
--
S
A
V
E
I
L
L
T
I
-------
D
D
-
T
K
--
R
A
------
G
M
------
K
-
E
--------
L
------
K
R
H
P
L
F
--
S
--
D
V
D
W
E
--
N
--
L
--
Q
--
H
--
Q
--
T
M
P
F
I
P
Q
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
359
Blastp_CBE
67.24
34%
-70
- C4 -
-
3OW3
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
224
Blastp_CBE
67.27
34%
-67
- C4 -
-
1Q8T
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
339
Blastp_CBE
67.25
34%
-68
- C4 -
-
1YDT
1
KAPCA_BOVIN
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
173
Blastp_CBE
67.24
34%
-75
- C4 -
-
5LCU
5
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
128
Blastp_CBE
67.23
35%
-70
- C4 -
-
4UJ2
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
369
Blastp_CBE
67.22
34%
-71
- C4 -
-
1ATP
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
370
Blastp_CBE
67.16
34%
-70
- C4 -
-
1JBP
2
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
E
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
223
Blastp_CBE
67.14
34%
-70
- C4 -
-
1Q8U
3
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
161
Blastp_CBE
67.15
34%
-66
- C4 -
-
5N1K
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
----
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
174
Blastp_CBE
67.14
34%
-71
- C4 -
-
5LCT
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
202
Blastp_CBE
67.12
34%
-66
- C4 -
-
4YXR
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKDGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
355
Blastp_CBE
67.11
34%
-75
- C4 -
-
1BKX
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
184
Blastp_CBE
67.10
34%
-72
- C4 -
-
6E99
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
183
Blastp_CBE
67.02
34%
-67
- C4 -
-
6E9L
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
Blastp_CBE
67.02
35%
-103
- C4 -
-
5LOH
2
GWL_HUMAN
A:
[33-316]
------------------------------------------------------------------------------------------------------
P
S
I
E
E
F
S
I
V
K
P
I
S
----
G
K
V
Y
L
G
Q
K
G
------
G
K
---
L
Y
A
V
K
V
V
K
K
A
D
M
---------------
L
A
-
L
S
-
K
S
-
P
F
I
V
H
L
Y
Y
S
L
Q
S
A
N
N
V
Y
L
V
M
E
Y
L
I
G
G
D
V
K
S
L
L
---
H
I
Y
-
G
Y
F
D
E
E
M
A
V
K
Y
I
S
E
V
A
L
A
L
D
Y
L
H
R
-
H
G
I
I
H
R
D
L
K
P
D
N
M
L
I
S
N
E
G
H
I
K
L
T
D
F
G
--
L
S
K
-----------
F
C
-
G
T
P
D
Y
L
A
P
E
L
L
L
-----
G
R
--
A
H
G
P
A
V
D
W
W
A
L
G
V
C
L
F
E
F
L
T
G
I
P
P
F
-
N
D
E
T
P
Q
Q
V
F
Q
---
N
I
L
------------
K
R
D
I
P
W
P
-----
E
G-
E
-
E
K
L
S
D
N
A
Q
--
S
A
V
E
I
L
L
T
I
-------
D
D
-
T
K
--
R
A
------
G
M
------
K
-
E
--------
L
------
K
R
H
P
L
F
--
S
--
D
V
D
W
E
--
N
--
L
--
Q
--
H
--
Q
--
T
M
P
F
I
P
Q
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137
Blastp_CBE
66.99
35%
-70
- C4 -
-
3L9L
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
164
Blastp_CBE
66.98
34%
-67
- C4 -
-
5MHI
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
150
Blastp_CBE
66.97
34%
-62
- C4 -
-
2UW4
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
-
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
153
Blastp_CBE
66.96
34%
-65
- C4 -
-
2JDT
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
117
Blastp_CBE
66.94
35%
-70
- C4 -
-
4UJB
3
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
158
Blastp_CBE
66.93
34%
-71
- C4 -
-
5N7U
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
149
Blastp_CBE
66.93
34%
-65
- C4 -
-
2UW7
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
264
Blastp_CBE
66.88
37%
-56
- C4 -
-
3E87
1
AKT2_HUMAN
A:
[3-308]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
277
Blastp_CBE
66.85
34%
-72
- C4 -
-
1SMH
6
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
E
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
L
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
167
Blastp_CBE
66.86
34%
-70
- C4 -
-
5M6Y
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
170
Blastp_CBE
66.85
34%
-69
- C4 -
-
5M0L
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
353
Blastp_CBE
66.81
34%
-67
- C4 -
-
3FHI
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
A
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109
Blastp_CBE
66.81
35%
-71
- C4 -
-
3L9M
1
KAPCA_HUMAN
B:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136
Blastp_CBE
66.79
35%
-71
- C4 -
-
3L9L
1
KAPCA_HUMAN
B:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
356
Blastp_CBE
66.75
34%
-69
- C4 -
-
2ERZ
1
KAPCA_MOUSE
E:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
246
Blastp_CBE
66.75
36%
-51
- C4 -
-
2JDO
2
AKT2_HUMAN
A:
[8-334]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
151
Blastp_CBE
66.73
34%
-67
- C4 -
-
2UVX
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
243
Blastp_CBE
66.71
36%
-55
- C4 -
-
2X39
1
AKT2_HUMAN
A:
[8-332]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
263
Blastp_CBE
66.69
37%
-57
- C4 -
-
3E87
1
AKT2_HUMAN
B:
[3-308]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
456
Blastp_CBE
66.68
33%
-72
- C4 -
-
1RDQ
3
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
A
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
175
Blastp_CBE
66.65
34%
-70
- C4 -
-
5LCR
5
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
177
Blastp_CBE
66.64
34%
-72
- C4 -
-
5LCP
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
152
Blastp_CBE
66.62
34%
-69
- C4 -
-
2JDV
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
157
Blastp_CBE
66.59
34%
-75
- C4 -
-
6F14
2
KAPCA_CRIGR
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
----
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
419
Blastp_CBE
66.54
33%
-71
- C4 -
-
3QAM
1
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
A
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
159
Blastp_CBE
66.58
34%
-71
- C4 -
-
5N7P
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
266
Blastp_CBE
66.54
37%
-56
- C4 -
-
3D0E
1
AKT2_HUMAN
A:
[3-307]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
225
Blastp_CBE
66.53
36%
-53
- C4 -
-
1O6K
1
AKT2_HUMAN
A:
[3-323]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
155
Blastp_CBE
66.44
34%
-62
- C4 -
-
2VO0
4
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
182
Blastp_CBE
66.34
35%
-67
- C4 -
-
4WB6
1
KAPCA_HUMAN
B:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
R
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
222
Blastp_CBE
66.30
34%
-72
- C4 -
-
1STC
1
KAPCA_BOVIN
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
232
Blastp_CBE
66.29
36%
-54
- C4 -
-
1O6L
1
AKT2_HUMAN
A:
[3-327]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
----------
R
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
377
Blastp_CBE
66.28
34%
-68
- C4 -
-
6MM7
9
KAPCA_MOUSE
D:
[32-339]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
379
Blastp_CBE
66.26
34%
-71
- C4 -
-
6MM6
1
KAPCA_MOUSE
E:
[32-339]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
Blastp_CBE
66.25
35%
-68
- C4 -
-
3L9M
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
383
Blastp_CBE
66.23
34%
-67
- C4 -
-
2GU8
1
KAPCA_HUMAN
A:
[36-318]
-----------------------------------------------------------------------------------------------------------------
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
E
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
576
HHSearch
66.20
33%
-28
- C4 -
-
5LI9
13
KPCI_HUMAN
A:
[4-343]
-------------------------------------------------------------------------------------------------------
G
L
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
S
N
H
-
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
Q
-
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
G
L
R
P
G
D
-
T
T
S
T
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
R
G
------
E
-
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
-----------TED
Y
L
F
----
Q
V
------
I
L
E
K
Q
I
R
-----
I
--
P
-
R
S
L
S
V
K
A
A
--
S
V
L
K
S
F
L
-
N
K------
D
P
-
K
E
--
R
L
------
G
C
HPQTGF
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
--
E
QK
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
-
Q
F
T
N
E
P
-
V
Q
L
T
-
P
D
D
D
D
I
---
V
R
K
-
I
D
Q
S
E
F
E
G
F
E
Y
I
N
P
L
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
245
Blastp_CBE
66.14
36%
-48
- C4 -
-
2JDR
1
AKT2_HUMAN
A:
[8-332]
-------------------------------------------------------------------------------------------------------
T
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
Q
-
N
T
-
R
H
-
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
-
L
C
K
E
G
I
S
D
---
G
A
T
M
K
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
R
L
F
E
---
L
I
L
----
M
E
------
E
--
I
R
F
P
-----
R
-----
T
L
S
P
E
A
K
--
S
L
L
A
G
L
L
-
K
-------
K
D
P
K
Q
--
R
L
GGGPS-
D
A
------
K
-
E
--------
V
------
M
E
H
R
F
F
--
L
--
S
I
N
W
Q
--
D
--
V
VQ
K
--
K
--
L
--
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
-
E
F
T
A
Q
S
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
148
Blastp_CBE
66.13
34%
-62
- C4 -
-
4AXA
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
376
Blastp_CBE
66.12
34%
-69
- C4 -
-
6MM8
5
KAPCA_MOUSE
C:
[32-339]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
375
Blastp_CBE
66.07
33%
-73
- C4 -
-
3O7L
2
KAPCA_MOUSE
B:
[43-335]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
---
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
I
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
I
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
240
Blastp_CBE
66.10
35%
-63
- C4 -
-
4WB7
1
KAPCA_HUMAN
B:
[98-386]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
G
R
F
S
-
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
147
Blastp_CBE
66.08
35%
-63
- C4 -
-
3MVJ
1
KAPCA_HUMAN
A:
[64-352]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
166
Blastp_CBE
66.07
34%
-75
- C4 -
-
5M71
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
241
Blastp_CBE
66.06
35%
-62
- C4 -
-
4WB7
1
DNJB1_HUMAN (first)
A:
[98-386]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
G
R
F
S
-
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
169
Blastp_CBE
65.92
34%
-71
- C4 -
-
5M0U
10
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
----
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
358
Blastp_CBE
65.87
34%
-68
- C4 -
-
4DIN
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
108
Blastp_CBE
65.65
35%
-77
- C4 -
-
3L9N
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
---
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
193
Blastp_CBE
65.59
34%
-78
- C4 -
-
5VIB
1
KAPCA_BOVIN
A:
[44-347]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
---------
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
571
HHSearch
65.58
33%
-63
- C4 -
-
1XJD
1
A:
[16-335]
--------------------------------------------------------------------------------------------------------
I
E
D
F
I
L
H
K
M
L
G
K
G
S
F
G
K
V
F
L
A
E
F
K
K
---
T
-
N
Q
---
F
F
A
I
K
A
L
K
K
D
V
V
L
M
D
D
D
V
E
C
T
M
V
E
K
R
V
L
S
L
A
W
-
E
H
-
P
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
---
Q
S
C
-
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
K
D
G
H
I
K
I
A
D
F
G
-
M
C
K
E
N
M
L
G
D
-
A
K
T
N
T
F
C
-
G
T
P
D
Y
I
A
P
E
I
L
L
G
------
Q
-
K
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
Q
S
P
F
-
H
G
Q
D
E
E
E
L
F
H
---
S
I
R
----
M
D
------
N
P
--
F
Y
P
----------
R
W
L
E
K
E
A
K
--
D
L
L
V
K
L
F
-
V
R------
E
P
-
E
K
--
R
L
------
G
V
------
R
G
D
--------
I
------
R
Q
H
P
L
F
--
R
--
E
I
N
W
E
--
E
--
L
--
E
RK
E
--
I
--
D
P
---------------------------------------------
Q
N
M
F
R
N
F
S
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
130
Blastp_CBE
65.20
35%
-70
- C4 -
-
3POO
2
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
----
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
420
Blastp_CBE
64.94
36%
-28
- C4 -
-
6CCY
1
AKT1_HUMAN
A:
[3-328]
----------------------------------------------------------------------------------------------------
L
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
S
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
P
-
S
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
457
Blastp_CBE
64.54
33%
-73
- C4 -
-
2QUR
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLPNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
A
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
192
Blastp_CBE
64.47
34%
-71
- C4 -
-
3AMA
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
R
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
Q
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
-----
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
503
Blastp_CBE
64.05
33%
-33
- C4 -
-
4DC2
1
KPCI_MOUSE
A:
[52-363]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
R
V
V
K
K
E
L
V
N
----
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
--
M
C
K
E
G
L
R
P
G
D
T
T
S
T
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
V
G
S
---------
N
T
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
402
Blastp_CBE
63.76
36%
-28
- C4 -
-
3CQU
1
AKT1_HUMAN
A:
[8-329]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
393
Blastp_CBE
63.76
36%
-24
- C4 -
-
3OCB
1
AKT1_HUMAN
A:
[7-331]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
399
Blastp_CBE
63.65
36%
-24
- C4 -
-
3MVH
1
AKT1_HUMAN
A:
[8-333]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
512
Blastp_CBE
63.55
33%
-19
- C4 -
-
6BDL
1
KGP1_HUMAN
A:
[35-332]
----------------------------------------------------------------------------------------------------------
D
F
N
I
I
D
T
L
G
V
G
G
F
G
R
V
E
L
V
Q
L
K
S
---
E
E
S
K
---
T
F
A
M
K
I
L
K
K
R
H
I
V
D
T
R
Q
Q
E
H
I
R
S
E
K
Q
I
M
Q
-
G
A
-
H
S
-
D
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
----
R
D
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
H
R
G
Y
A
K
L
V
D
F
G
-
F
A
K
K
I
G
F
G
K
---
K
T
W
F
C
-
G
T
P
E
Y
V
A
P
E
I
--
I
L
N
---
K
G
--
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
S
P
P
F
-
S
G
P
D
P
M
K
T
Y
N
---
I
I
L
----
R
G
------
I
D
M
I
E
F
P
-----
K
-----
K
I
A
K
N
A
A
--
N
L
I
K
K
-
L
-
C
RD-----
N
P
-
S
E
--
R
L
GNLKN-
G
V
------
K
-
D
--------
I
------
Q
K
H
K
W
F
--
E
--
G
F
N
W
E
--
G
--
L
--
R
--
K
--
G
TL
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
F
P
E
D
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
386
Blastp_CBE
63.50
36%
-23
- C4 -
-
4EKK
1
AKT1_HUMAN
A:
[7-327]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
400
Blastp_CBE
63.49
36%
-24
- C4 -
-
3MV5
1
AKT1_HUMAN
A:
[8-339]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
390
Blastp_CBE
63.46
36%
-24
- C4 -
-
3OW4
1
AKT1_HUMAN
B:
[7-339]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
392
Blastp_CBE
63.40
36%
-21
- C4 -
-
3OCB
1
AKT1_HUMAN
B:
[7-327]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
511
Blastp_CBE
63.35
33%
-18
- C4 -
-
6BDL
1
KGP1_HUMAN
B:
[35-332]
----------------------------------------------------------------------------------------------------------
D
F
N
I
I
D
T
L
G
V
G
G
F
G
R
V
E
L
V
Q
L
K
S
---
E
E
S
K
---
T
F
A
M
K
I
L
K
K
R
H
I
V
D
T
R
Q
Q
E
H
I
R
S
E
K
Q
I
M
Q
-
G
A
-
H
S
-
D
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
----
R
D
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
H
R
G
Y
A
K
L
V
D
F
G
-
F
A
K
K
I
G
F
G
K
---
K
T
W
F
C
-
G
T
P
E
Y
V
A
P
E
I
--
I
L
N
---
K
G
--
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
S
P
P
F
-
S
G
P
D
P
M
K
T
Y
N
---
I
I
L
----
R
G
------
I
D
M
I
E
F
P
-----
K
-----
K
I
A
K
N
A
A
--
N
L
I
K
K
-
L
-
C
RD-----
N
P
-
S
E
--
R
L
GNLKN-
G
V
------
K
-
D
--------
I
------
Q
K
H
K
W
F
--
E
--
G
F
N
W
E
--
G
--
L
--
R
--
K
--
G
TL
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
F
P
E
D
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
385
Blastp_CBE
63.24
36%
-20
- C4 -
-
4EKK
1
AKT1_HUMAN
B:
[7-327]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
191
Blastp_CBE
63.16
34%
-65
- C4 -
-
3AMB
1
KAPCA_HUMAN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
R
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
Q
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
A
P
G
G
E
M
F
S
H
L
---
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
K
V
A
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
-----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
-----
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
401
Blastp_CBE
63.05
36%
-21
- C4 -
-
3CQW
1
AKT1_HUMAN
A:
[8-329]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
391
Blastp_CBE
62.97
36%
-24
- C4 -
-
3OW4
1
AKT1_HUMAN
A:
[7-339]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
398
Blastp_CBE
62.96
36%
-23
- C4 -
-
6NPZ
2
AKT1_HUMAN
A:
[24-344]
-------------------------------------------------------------------------------------------------------
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
E
K
A
---
T
-
G
R
---
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
-
N
S
-
R
H
-
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
---
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
--
L
C
K
E
G
I
K
D
G
A
T
M
K
F
-
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
-
Y
N
Q
D
H
E
K
L
F
E
---
L
I
L
MEEI
R
F
------
P
R
T
L
G
-
P
-----
E
--
A
-
K
S
L
L
S
G
L
L
KK
D
P
K
Q
R
L
G
-
G
-------
G
S
-
E
D
--
A
---------------
K
-
E
--------
I
------
M
Q
H
R
F
F
--
A
--
G
I
V
W
Q
--
H
--
V
YE
K
--
K
--
L
--
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
-
E
F
T
A
Q
M
-
I
T
I
T
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
506
Blastp_CBE
62.47
33%
-13
- C4 -
-
6C0T
3
KGP1_HUMAN
A:
[35-332]
----------------------------------------------------------------------------------------------------------
D
F
N
I
I
D
T
L
G
V
G
G
F
G
R
V
E
L
V
Q
L
K
S
---
E
E
S
K
---
T
F
A
M
K
I
L
K
K
R
H
I
V
D
T
R
Q
Q
E
H
I
R
S
E
K
Q
I
M
Q
-
G
A
-
H
S
-
D
F
I
V
R
L
Y
R
T
F
K
D
S
K
Y
L
Y
M
L
M
E
A
C
L
G
G
E
L
W
T
I
L
----
R
D
R
G
S
F
E
D
S
T
T
R
F
Y
T
A
C
V
V
E
A
F
A
Y
L
H
S
-
K
G
I
I
Y
R
D
L
K
P
E
N
L
I
L
D
H
R
G
Y
A
K
L
V
D
F
G
-
F
A
K
K
I
G
F
G
K
---
K
T
W
F
C
-
G
T
P
E
Y
V
A
P
E
I
--
I
L
N
---
K
G
--
H
D
I
S
A
D
Y
W
S
L
G
I
L
M
Y
E
L
L
T
G
S
P
P
F
-
S
G
P
D
P
M
K
T
Y
N
---
I
I
L
----
R
G
------
I
D
M
I
E
F
P
-----
K
-----
K
I
A
K
N
A
A
--
N
L
I
K
K
-
L
-
C
RD-----
N
P
-
S
E
--
R
L
GNLKN-
G
V
------
K
-
D
--------
I
------
Q
K
H
K
W
F
--
E
--
G
F
N
W
E
--
G
--
L
--
R
--
K
--
G
TL
T
P
P
I
I
P
S
V
A
S
P
T
D
T
S
N
F
D
S
F
P
E
D
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
348
Blastp_CBE
61.75
34%
-25
- C4 -
-
2JDS
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
247
Blastp_CBE
61.58
34%
-26
- C4 -
-
4WB8
2
KAPCA_HUMAN
A:
[30-318]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
346
Blastp_CBE
61.49
34%
-24
- C4 -
-
3ZO3
9
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
445
Blastp_CBE
61.47
33%
-34
- C4 -
-
4IAK
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
272
Blastp_CBE
61.39
34%
-28
- C4 -
-
6EM7
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
347
Blastp_CBE
61.38
34%
-23
- C4 -
-
3ZO1
7
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
352
Blastp_CBE
61.37
34%
-30
- C4 -
-
1Q8W
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
297
Blastp_CBE
61.28
34%
-29
- C4 -
-
5OUC
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
350
Blastp_CBE
61.24
34%
-20
- C4 -
-
3BWJ
2
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
229
Blastp_CBE
61.22
34%
-27
- C4 -
-
4WB5
1
KAPCA_HUMAN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
335
Blastp_CBE
61.14
34%
-24
- C4 -
-
5N1F
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
299
Blastp_CBE
61.16
34%
-28
- C4 -
-
5OTG
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
325
Blastp_CBE
61.14
34%
-24
- C4 -
-
5N39
5
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
443
Blastp_CBE
61.06
33%
-28
- C4 -
-
4IAZ
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
333
Blastp_CBE
61.08
34%
-22
- C4 -
-
5N1H
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
282
Blastp_CBE
61.10
34%
-28
- C4 -
-
6I2A
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
468
Blastp_CBE
61.03
33%
-26
- C4 -
-
4DG3
1
KAPCA_MOUSE
E:
[64-352]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
278
Blastp_CBE
61.08
34%
-24
- C4 -
-
6I2H
1
?
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
334
Blastp_CBE
61.06
34%
-22
- C4 -
-
5N1G
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
441
Blastp_CBE
61.04
33%
-25
- C4 -
-
4IB1
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
288
Blastp_CBE
61.03
34%
-22
- C4 -
-
6EMD
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
323
Blastp_CBE
61.02
34%
-19
- C4 -
-
5N3B
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
349
Blastp_CBE
61.01
34%
-24
- C4 -
-
3KKV
1
KAPCA_BOVIN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
289
Blastp_CBE
60.98
34%
-28
- C4 -
-
6EMB
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
488
Blastp_CBE
60.95
37%
8
- C4 -
-
4NW5
1
KS6A3_HUMAN
A:
[32-322]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
I
D
H
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
-------
T
F
Y
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
315
Blastp_CBE
60.94
34%
-20
- C4 -
-
5N3J
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
248
Blastp_CBE
60.91
34%
-20
- C4 -
-
2VO6
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
437
Blastp_CBE
60.90
33%
-26
- C4 -
-
4XW6
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
442
Blastp_CBE
60.84
33%
-24
- C4 -
-
4IB0
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
428
Blastp_CBE
60.84
33%
-28
- C4 -
-
4DH7
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
309
Blastp_CBE
60.85
34%
-21
- C4 -
-
5N3Q
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
255
Blastp_CBE
60.87
34%
-21
- C4 -
-
2UW3
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
254
Blastp_CBE
60.86
34%
-22
- C4 -
-
2UW5
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
286
Blastp_CBE
60.85
34%
-25
- C4 -
-
6ERT
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
326
Blastp_CBE
60.84
34%
-22
- C4 -
-
5N37
6
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
328
Blastp_CBE
60.81
34%
-23
- C4 -
-
5N33
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
446
Blastp_CBE
60.83
33%
-25
- C4 -
-
4IAI
2
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
279
Blastp_CBE
60.81
34%
-22
- C4 -
-
6I2D
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
318
Blastp_CBE
60.78
34%
-21
- C4 -
-
5N3G
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
307
Blastp_CBE
60.80
34%
-22
- C4 -
-
5N3S
5
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
290
Blastp_CBE
60.78
34%
-25
- C4 -
-
6EMA
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
487
Blastp_CBE
60.75
37%
10
- C4 -
-
4NW6
1
KS6A3_HUMAN
A:
[32-322]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
I
D
H
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
-------
T
F
Y
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
455
Blastp_CBE
60.74
33%
-29
- C4 -
-
4DFX
4
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
433
Blastp_CBE
60.68
33%
-27
- C4 -
-
4DG0
2
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
283
Blastp_CBE
60.72
34%
-25
- C4 -
-
6ESA
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
250
Blastp_CBE
60.68
34%
-20
- C4 -
-
2VNY
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
422
Blastp_CBE
60.66
33%
-25
- C4 -
-
1L3R
3
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
448
Blastp_CBE
60.60
33%
-28
- C4 -
-
4IAD
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
331
Blastp_CBE
60.61
34%
-22
- C4 -
-
5N1M
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
450
Blastp_CBE
60.57
33%
-27
- C4 -
-
3X2W
1
KAPCA_MOUSE
A:
[50-338]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
426
Blastp_CBE
60.57
33%
-26
- C4 -
-
4HPU
2
KAPCA_MOUSE
E:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
300
Blastp_CBE
60.61
34%
-27
- C4 -
-
5OT3
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
405
Blastp_CBE
60.60
33%
-27
- C4 -
-
4C35
2
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
Y
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
304
Blastp_CBE
60.57
34%
-26
- C4 -
-
5O0E
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
332
Blastp_CBE
60.54
34%
-19
- C4 -
-
5N1L
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
324
Blastp_CBE
60.56
34%
-22
- C4 -
-
5N3A
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
327
Blastp_CBE
60.54
34%
-22
- C4 -
-
5N36
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
407
Blastp_CBE
60.49
33%
-22
- C4 -
-
4C38
4
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
Y
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
449
Blastp_CBE
60.47
33%
-25
- C4 -
-
4IAC
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
404
Blastp_CBE
60.47
33%
-24
- C4 -
-
4C36
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
Y
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
291
Blastp_CBE
60.50
34%
-22
- C4 -
-
6EM6
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
256
Blastp_CBE
60.49
34%
-21
- C4 -
-
2UW0
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
343
Blastp_CBE
60.47
34%
-25
- C4 -
-
3ZO2
4
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
431
Blastp_CBE
60.42
33%
-26
- C4 -
-
4DH1
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
320
Blastp_CBE
60.46
34%
-20
- C4 -
-
5N3E
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
429
Blastp_CBE
60.39
33%
-24
- C4 -
-
4DH5
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
336
Blastp_CBE
60.42
34%
-24
- C4 -
-
4WB6
1
KAPCA_HUMAN
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
R
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
329
Blastp_CBE
60.41
34%
-27
- C4 -
-
5N1O
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
-
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
447
Blastp_CBE
60.40
33%
-26
- C4 -
-
4IAF
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
310
Blastp_CBE
60.39
34%
-21
- C4 -
-
5N3P
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
434
Blastp_CBE
60.38
33%
-26
- C4 -
-
2QCS
5
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
314
Blastp_CBE
60.37
34%
-21
- C4 -
-
5N3K
5
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
322
Blastp_CBE
60.36
34%
-17
- C4 -
-
5N3C
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
313
Blastp_CBE
60.35
34%
-23
- C4 -
-
5N3L
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
489
Blastp_CBE
60.22
37%
2
- C4 -
-
4NUS
1
KS6A3_HUMAN
A:
[32-322]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
I
D
H
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
A
------
T
F
Y
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
452
Blastp_CBE
60.34
33%
-29
* C4 *
-
3X2U
1
KAPCA_MOUSE
A:
[50-338]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
440
Blastp_CBE
60.33
33%
-25
- C4 -
-
4IB3
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
305
Blastp_CBE
60.30
34%
-24
- C4 -
-
5NTJ
2
KAPCA_CRIGR
A:
[46-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
293
Blastp_CBE
60.30
34%
-27
- C4 -
-
6EH3
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
302
Blastp_CBE
60.28
34%
-26
- C4 -
-
5OK3
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
252
Blastp_CBE
60.28
34%
-19
- C4 -
-
2UW8
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
311
Blastp_CBE
60.25
34%
-18
- C4 -
-
5N3O
6
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
436
Blastp_CBE
60.26
33%
-27
- C4 -
-
6E21
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
439
Blastp_CBE
60.20
33%
-24
- C4 -
-
4XW4
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
292
Blastp_CBE
60.25
34%
-22
- C4 -
-
6EM2
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
301
Blastp_CBE
60.24
34%
-22
- C4 -
-
5OL3
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
317
Blastp_CBE
60.20
34%
-19
- C4 -
-
5N3H
4
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
451
Blastp_CBE
60.22
33%
-26
- C4 -
-
3X2V
1
KAPCA_MOUSE
A:
[50-338]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
275
Blastp_CBE
60.20
34%
-27
- C4 -
-
5NW8
2
KAPCA_CRIGR
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
444
Blastp_CBE
60.19
33%
-29
- C4 -
-
4IAY
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
319
Blastp_CBE
60.16
34%
-23
- C4 -
-
5N3F
3
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
--
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
-
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
321
Blastp_CBE
60.15
34%
-19
- C4 -
-
5N3D
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
408
Blastp_CBE
60.13
33%
-22
- C4 -
-
4C37
2
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
Y
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
253
Blastp_CBE
60.07
34%
-23
- C4 -
-
2UW6
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
258
Blastp_CBE
60.03
34%
-21
- C4 -
-
2UVY
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
284
Blastp_CBE
60.02
34%
-28
- C4 -
-
6ERW
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
---
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
438
Blastp_CBE
59.93
33%
-26
- C4 -
-
4XW5
1
KAPCA_MOUSE
A:
[49-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
435
Blastp_CBE
59.93
33%
-31
- C4 -
-
3PVB
1
KAPCA_MOUSE
A:
[38-326]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
430
Blastp_CBE
59.93
33%
-25
- C4 -
-
4DH3
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
251
Blastp_CBE
59.93
34%
-21
- C4 -
-
2VNW
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
249
Blastp_CBE
59.87
34%
-22
- C4 -
-
2VO3
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
287
Blastp_CBE
59.86
34%
-23
- C4 -
-
6ERS
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
--
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
280
Blastp_CBE
59.82
34%
-22
- C4 -
-
6I2C
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
--
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
427
Blastp_CBE
59.76
33%
-25
- C4 -
-
4DH8
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
486
Blastp_CBE
59.80
37%
2
- C4 -
-
5D9L
2
KS6A3_HUMAN
A:
[32-322]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
-------------
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
A
T
G
R
P
E
D
T
F
Y
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
257
Blastp_CBE
59.77
34%
-23
- C4 -
-
2UVZ
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
T
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
A
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
423
Blastp_CBE
59.76
33%
-26
- C4 -
-
5JR7
1
KAPCA_MOUSE
C:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
421
Blastp_CBE
59.73
33%
-29
- C4 -
-
3TNQ
1
KAPCA_MOUSE
B:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
424
Blastp_CBE
59.59
33%
-26
- C4 -
-
5JR7
1
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
499
Blastp_CBE
59.44
33%
-27
- C4 -
-
3ZH8
5
KPCI_HUMAN
B:
[5-342]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
V
G
-----------
T
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
491
Blastp_CBE
59.48
37%
-10
- C4 -
-
5D9K
2
KS6A3_HUMAN
A:
[32-323]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
------------
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
A
------
T
F
Y
F
D
--
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
453
Blastp_CBE
59.47
33%
-23
- C4 -
-
4X6R
5
KAPCA_MOUSE
A:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
464
Blastp_CBE
59.44
34%
-24
- C4 -
-
4O21
1
KAPCA_MOUSE
A:
[41-323]
-----------------------------------------------------------------------------------------------------------------
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
490
Blastp_CBE
59.42
37%
-1
- C4 -
-
5D9K
2
KS6A3_HUMAN
B:
[32-323]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
T
-
K
M
E
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
-----------
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
P
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
-------
T
F
Y
F
D
--
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
425
Blastp_CBE
59.22
33%
-23
- C4 -
-
4WBB
1
KAPCA_MOUSE
B:
[43-331]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
S
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
345
Blastp_CBE
59.09
34%
-24
- C4 -
-
5VHB
1
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
-----
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
281
Blastp_CBE
59.02
34%
-19
- C4 -
-
6I2B
2
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
295
Blastp_CBE
58.81
34%
-25
- C4 -
-
6EGW
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
-------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
P
-
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
406
Blastp_CBE
58.71
33%
-24
- C4 -
-
4C34
3
KAPCA_BOVIN
A:
[44-332]
-----------------------------------------------------------------------------------------------------------
F
E
R
I
K
T
L
G
T
G
S
Y
G
R
V
M
L
V
K
H
M
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
L
E
Y
L
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
M
I
D
Q
Q
G
Y
I
K
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
-
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
303
Blastp_CBE
58.59
34%
-20
- C4 -
-
5O5M
1
KAPCA_CRIGR
A:
[46-334]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
529
Blastp_CBE
58.51
33%
-30
- C4 -
-
3A8W
1
KPCI_HUMAN
B:
[9-320]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
---
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
--------------
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
294
Blastp_CBE
58.38
34%
-23
- C4 -
-
6EH2
2
KAPCA_CRIGR
A:
[46-337]
-----------------------------------------------------------------------------------------------------------
F
D
R
I
K
T
L
---
S
F
G
R
V
M
L
V
K
H
K
E
---
T
-
G
N
---
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
-
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
RRI
G
R
F
E
P
H
-----
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
-
F
A
K
R
V
K
G
R
T
W
L
T
----
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
--
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
A
D
Q
P
I
Q
I
Y
E
---
K
I
V
----
S
G
------
K
--
V
R
F
P
-----
S
-----
H
F
S
S
D
L
K
--
D
L
L
R
N
L
L
----------
Q
-
V
D
--
L
T
------
K
R
------
F
-
G
NLKNGVND
I
------
K
N
H
K
W
F
--
A
--
T
T
D
W
I
--
A
--
I
YQ
R
--
K
--
V
--
E
A
P
F
I
P
K
F
K
G
--
D
T
S
N
F
D
D
-
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
525
Blastp_CBE
58.27
33%
-34
- C4 -
-
6ILZ
1
KPCI_HUMAN
C:
[11-320]
-----------------------------------------------------------------------------------------------------------
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
-------
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
-------------------
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
--
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
467
Blastp_CBE
58.25
38%
-18
- C4 -
-
2Z7Q
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
T
RPD
S
-
G
H
---
L
Y
A
M
K
V
L
-------------------
I
L
A
-
D
V
-
N
H
-
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
---
V
V
N
R
Q
G
----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
L
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
T
E
A
Q
--
S
L
L
R
A
L
F
-
K
R------
N
P
-
A
N
--
R
L
GSGPD-
G
A
------
E
-
E
--------
I
------
K
R
H
V
F
Y
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
K
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
522
Blastp_CBE
58.01
33%
-22
- C4 -
-
5LI9
13
KPCI_HUMAN
A:
[6-317]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D---------------
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
530
Blastp_CBE
57.62
33%
-31
- C4 -
-
3A8W
1
KPCI_HUMAN
A:
[9-320]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
N
----
I
D
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
--------------
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
466
Blastp_CBE
57.43
38%
-1
- C4 -
-
2Z7R
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
T
RPD
S
-
G
H
---
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
------------
I
L
A
-
D
V
-
N
H
-
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
---
V
V
N
R
Q
G
----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
L
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
T
E
A
Q
--
S
L
L
R
A
L
F
-
K
R------
N
P
-
A
N
--
R
L
GSGPD-
G
A
------
E
-
E
--------
I
------
K
R
H
V
F
Y
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
K
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
465
Blastp_CBE
57.39
38%
-10
- C4 -
-
2Z7S
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
T
RPD
S
-
G
H
---
L
Y
A
M
K
V
L
K
------------------
I
L
A
-
D
V
-
N
H
-
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
---
V
V
N
R
Q
G
----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
L
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
T
E
A
Q
--
S
L
L
R
A
L
F
-
K
R------
N
P
-
A
N
--
R
L
GSGPD-
G
A
------
E
-
E
--------
I
------
K
R
H
V
F
Y
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
K
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
515
Blastp_CBE
57.38
37%
-17
- C4 -
-
3UBD
1
KS6A3_MOUSE
A:
[26-304]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
-------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
-----
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
FL
S
-
P
E
A
Q
S
------
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
473
Blastp_CBE
57.13
38%
11
- C4 -
-
6G77
2
KS6A6_HUMAN
A:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
R
D
---------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
D
Q
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
M
N
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
505
Blastp_CBE
57.03
37%
-9
- C4 -
-
4EL9
1
KS6A3_MOUSE
A:
[27-305]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
------
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
---
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
FL
S
-
P
E
A
Q
S
------
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
514
Blastp_CBE
56.75
33%
-30
- C4 -
-
5LIH
3
KPCI_HUMAN
A:
[5-316]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
V
-------
W
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
V
-----------
N
T
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
472
Blastp_CBE
56.73
38%
13
- C4 -
-
6G77
2
KS6A6_HUMAN
B:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
R
D
---------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
D
Q
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
M
N
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
504
Blastp_CBE
56.42
37%
-13
- C4 -
-
4GUE
1
KS6A3_MOUSE
A:
[27-305]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
---------
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
-----
E
K
K
A
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
FL
S
-
P
E
A
Q
S
------
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
483
Blastp_CBE
56.25
38%
-5
- C4 -
-
3G51
1
KS6A3_MOUSE
A:
[26-304]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
S
---
G
-
S
D
ARQ
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
----------
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
---
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
I
------------
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
K
E
T
M
T
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
FL
S
-
P
E
A
Q
S
------
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
GAGPD-
G
V
------
E
-
E
--------
I
------
K
R
H
S
F
F
--
S
--
T
I
D
W
N
--
K
--
L
YR
R
--
E
--
I
--
H
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
475
Blastp_CBE
55.80
38%
4
- C4 -
-
6G78
1
KS6A6_HUMAN
B:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
R
D
---------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
-----------
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
M
N
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
485
Blastp_CBE
55.31
38%
-16
- C4 -
-
6G76
2
KS6A6_HUMAN
A:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
R
D
---------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
D
Q
E
K
K
A
Y
F
-
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
M
N
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
476
Blastp_CBE
55.22
38%
7
- C4 -
-
6G78
1
KS6A6_HUMAN
A:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
R
D
---------
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
D
Q
---------
G
T
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
M
N
---
M
I
L
----
K
A
------
K
--
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
513
Blastp_CBE
54.73
33%
-25
- C4 -
-
5LIH
3
KPCI_HUMAN
B:
[5-316]
---------------------------------------------------------------------------------------------------------
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
L
K
K
---
T
-
D
R
---
I
Y
A
M
K
V
V
K
K
E
L
---------
V
Q
T
E
K
H
V
F
E
-
Q
A
-
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
---
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
-
M
C
K
E
--
G
L
R
P
G
D
T
T
S
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
-------
R
G
E
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
I
--------------
E
----
D
Y
LFQVIL
E
K
Q
I
R
I
P
-----
R
--
S
-
L
S
V
K
A
--
A
--
S
V
L
K
S
F
L
-
N
-------
K
D
P
K
E
--
R
L
GCHPQT
G
F
------
A
-
D
--------
I
------
Q
G
H
P
F
F
--
R
--
N
V
D
W
D
--
M
--
M
EQ
K
--
Q
--
V
--
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
------
S
Q
-
F
T
N
E
-
P
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
484
Blastp_CBE
53.82
38%
-1
- C4 -
-
6G76
1
KS6A6_HUMAN
B:
[31-307]
-----------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
K
T
GPD
A
-
G
Q
---
L
Y
A
M
K
V
L
K
K
A
S
L
K
V
----------
R
D
I
L
V
-
E
V
-
N
H
-
P
F
I
V
K
L
H
Y
A
F
Q
T
--
K
L
Y
L
I
L
D
F
L
R
G
G
D
V
F
T
R
L
---
S
K
-
E
V
L
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
Q
-
L
G
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
E
I
G
H
I
K
L
T
D
F
G
--
L
S
K
E
S
V
D
------------
V
E
Y
M
A
P
E
V
V
N
------
R
R
-
G
H
S
Q
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
T
L
P
F
-
Q
G
K
D
R
N
E
T
-----------------------
L
G
M
P
-----
Q
-----
F
L
S
A
E
A
Q
--
S
L
L
R
M
L
F
-
K
R------
N
P
-
A
N
--
R
L
------
G
S
------
E
-
G
VEE-----
I
------
K
R
H
L
F
F
--
A
--
N
I
D
W
D
--
K
--
L
YK
R
--
E
--
V
--
Q
P
P
F
K
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------