@TOME V3
(Feb 2022)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : TTBK1_HUMAN: (2019-05-28 )
MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGAR
Atome Classification :
(9 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
Q
C
L
A
A
A
L
KDETNMSGGGEQ
A
D
ILPANY
V
V
K
D
R
W
K
V
L
K
K
IGGG
G
F
G
E
I
Y
E
A
M
D
L
L
TRE
N
V
A
L
K
VESAQ
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
LQG
K
D
H
V
C
R
F
IGCGRN
E
K
F
N
Y
V
V
M
Q
LQGR
N
L
A
D
L
RRSQPR
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
HRDIKPSNFAMGRL
P
S
T
Y
R
K
C
Y
M
LDFG
L
A
R
Q
YTNTTGDVRPPRNVAGFR
G
T
V
R
Y
A
S
VNAHKNREMGRH
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
VGQL
P
W
R
KIK
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
HMP
S
E
F
H
L
F
L
D
H
I
A
SLDYFTKP
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
ERGIAENEAFDWEKAGTD
A
L
LSTSTSTPPQQ
N
T
R
Q
T
A
A
M
F
G
V
V
NVTPV
P
G
D
L
L
REN
T
E
D
V
LQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNR
N
K
L
R
I
NIGKSPC
V
E
E
E
Q
SRGMGVPSSPVRAPPDSPTT
P
V
R
S
L
R
Y
RRVNSP
E
S
ERLSTADG
R
V
EL
P
E
R
RSRMDLPGSPS
R
Q
A
C
SSQP
A
Q
M
L
S
VDTGHADRQASGRMDV
S
A
S
V
E
Q
E
A
L
S
N
A
F
RSVPLAEEEDFDSK
E
W
V
I
IDKETELKDFPPGAEPSTSGTTDEE
P
E
E
LRPLPEE
G
E
E
R
R
RLGAEPTVRPRG
R
S
M
Q
A
L
A
E
E
D
L
Q
HLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQR
Q
V
F
SVAPPFEVNGLPRAVPLSL
P
Y
Q
D
F
K
R
D
L
S
D
Y
R
E
R
A
R
L
L
N
R
V
R
R
VGFS
H
M
L
L
TTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDE
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
E
A
A
A
A
V
A
L
G
E
V
LGPRSGSSSEGSERSTDRSQEGAPSTLLADD
Q
K
ESRGRASMADGDLEPEEG
S
K
T
L
V
L
VSPGDMKKSPVTAELAPDPDLG
T
L
A
ALTPQHERPQPTGSQLDVSEP
G
T
L
S
S
V
L
KSEPKPPGPGAGLGA
G
T
V
TTGVG
G
V
A
VTSSP
F
T
K
V
E
R
T
F
V
H
I
AE
K
T
H
L
N
V
MSSGGQ
A
L
R
S
EEFSAGGEL
G
L
E
LASDGGAVEEGARAPLENG
L
A
LSGLNGAEIEGSALSGAPRE
T
P
S
E
M
ATNSLPNGPALADGPAPVSPLEPSPE
K
V
A
TISPRRHAMPGSRPRSRI
P
V
L
L
SEEDTGSEPSGS
L
S
A
K
E
R
W
S
KRAR
P
Q
Q
D
L
A
R
L
V
M
E
KRQ
G
R
L
L
L
R
L
ASGASSS
S
S
E
E
Q
R
R
A
S
ETLSGTGSEEDTPASE
P
A
A
ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAA
P
A
L
D
T
A
I
TS
R
L
Q
L
QTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASP
R
S
QSLSRRESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRG
K
L
Q
A
QRATTKGRAGGAEGRAGAR
25
HHSearch
97.62
100%
-106
- C3 -
-
4NFN
1
TTBK1_HUMAN
A:
[11-303]
---------------------
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
97.42
99%
-106
- C3 -
-
4NFN
1
TTBK1_HUMAN
A:
[11-303]
---------------------
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Blastp_CBE
96.77
100%
-107
- C3 -
-
4BTJ
1
TTBK1_HUMAN
B:
[45-337]
--------------------
A
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
96.64
100%
-109
- C3 -
-
4BTK
2
TTBK1_HUMAN
A:
[46-335]
---------------------
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
---
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
96.64
100%
-109
- C3 -
-
4BTK
2
TTBK1_HUMAN
A:
[46-335]
---------------------
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
---
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
96.31
100%
-107
- C3 -
-
4BTJ
1
TTBK1_HUMAN
B:
[45-336]
--------------------
A
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.86
100%
-105
- C3 -
-
4BTJ
1
TTBK1_HUMAN
A:
[45-336]
--------------------
A
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Blastp_CBE
95.79
100%
-105
- C3 -
-
4BTM
3
TTBK1_HUMAN
B:
[45-337]
--------------------
A
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
95.77
100%
-106
- C3 -
-
4BTM
1
TTBK1_HUMAN
A:
[45-336]
--------------------
A
D
I
L
P
A
N
Y
V
V
K
D
R
W
K
V
L
K
K
I
G
G
G
G
F
G
E
I
Y
E
A
M
D
L
L
T
R
E
N
V
A
L
K
V
E
S
A
Q
Q
P
K
Q
V
L
K
M
E
V
A
V
L
K
K
L
Q
G
K
D
H
V
C
R
F
I
G
C
G
R
N
E
K
F
N
Y
V
V
M
Q
L
Q
G
R
N
L
A
D
L
R
R
S
Q
P
R
G
T
F
T
L
S
T
T
L
R
L
G
K
Q
I
L
E
S
I
E
A
I
H
S
V
G
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
L
P
S
T
Y
R
K
C
Y
M
L
D
F
G
L
A
R
Q
Y
T
N
T
T
G
D
V
R
P
P
R
N
V
A
G
F
R
G
T
V
R
Y
A
S
V
N
A
H
K
N
R
E
M
G
R
H
D
D
L
W
S
L
F
Y
M
L
V
E
F
A
V
G
Q
L
P
W
R
K
I
K
D
K
E
Q
V
G
M
I
K
E
K
Y
E
H
R
M
L
L
K
H
M
P
S
E
F
H
L
F
L
D
H
I
A
S
L
D
Y
F
T
K
P
D
Y
Q
L
I
M
S
V
F
E
N
S
M
K
E
R
G
I
A
E
N
E
A
F
D
W
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------