Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWR--GGDVAVKIFSSREERSWF-----REAEIYQTVMLRHENILGFIAADNKDNGTWTQ-LWLVSDYHEH---GSLFDYLNRYTVT-IEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQ--RVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI 3BLQ Chain:A ((26-207)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQ--LLKHENVVNLIEICRT-------SIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLN---GLYYIH--------RNKILHRDMKAANVLITRDGVLKLADFGLA---RAFS-------NRYNRVVTLWYRPPELL-----------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3BLQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 578 -17578 -30.41 -122.07 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -30.41 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.094

(partial model without unconserved sides chains): PDB file : Tito_3BLQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3blq-query.scw PDB file : Tito_Scwrl_3BLQ.pdb: