Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLGSLGLWALLPTAVEAPPNRRTCVFFEAPGVRGSTKTLGELLDTGTELPRAIRCLYSRCCFGIWNLTQDRAQVEMQGCRDSDEPGCESLHCDPSPRAHPSPGSTLFTCSCGTDFCNANYSHLPPPGSPGTPGSQGPQAAPGESIWMALVLLGLFLLLLLLLGSIILALLQRKNYRVRGEPVPEPRPDSGRDWSVELQELPELCFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITA---SRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPD--LRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRLAALAHPQESHPFPESCPRGCPPLCPEDCTSIPAPTILPCRPQRSACHFSVQQGPCSRNPQPACTLSPV 6EIX Chain:A ((38-329)) ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLW----LITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIF-GTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLA-VMHSQSTNQLDVGNNPR-------VGTKRYMAPEVLDETIQV-DCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDV-----VPNDPSFEDMRKVVCVDQQRPNIPNRW---FSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI-----------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 6EIX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1471 -57137 -38.84 -200.48 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -38.84 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.226

(partial model without unconserved sides chains): PDB file : Tito_6EIX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6eix-query.scw PDB file : Tito_Scwrl_6EIX.pdb: